Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.00145nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0398nMAssay Description:Displacement of [3H]GR113808 from human 5-HT4B receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0427nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0501nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0525nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0537nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0646nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0741nMAssay Description:Antagonistic activity at human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0794nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]GR113808 from human 5-HT4B receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.102nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.107nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.126nMAssay Description:Displacement of [3H]GR113808 from human 5-HT4B receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.141nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.195nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.234nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.339nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.339nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.759nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [125I]SB207710 from 5-HT4 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.813nMAssay Description:Antagonistic activity at human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [125I]SB207710 from 5-HT4 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Displacement of [125I]SB207710 from 5-HT4 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 107nMAssay Description:Antagonistic activity at human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 316nMAssay Description:Binding affinity to 5HT2B receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 398nMAssay Description:Binding affinity to opioid receptor Sigma1More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 501nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 794nMAssay Description:Displacement of [125I]SB207710 from 5-HT4 receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair