Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 4
Ligand
BDBM50442804
Substrate
n/a
Meas. Tech.
ChEMBL_989988 (CHEMBL2447593)
Ki
63±n/a nM
Citation
 Brudeli, B; Andressen, KW; Moltzau, LR; Nilsen, NO; Levy, FO; Klaveness, J Acidic biphenyl derivatives: synthesis and biological activity of a new series of potent 5-HT(4) receptor antagonists. Bioorg Med Chem 21:7134-45 (2013) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 4
Synonyms:
5-HT4 | 5-hydroxytryptamine receptor 4 | 5HT4R_CAVPO | HTR4 | Serotonin 4 (5-HT4) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
43735.29
Organism:
GUINEA PIG
Description:
5-HT4 HTR4 GUINEA PIG::O70528
Residue:
388
Sequence:
MDKLDANVSSKEGFGSVEKVVLLTFLSAVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWVYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHARQIQVLQRAGAPAEGRPQPADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQLWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRDTVECGGQWESQCHPAASSPLVAAQPIDT
  
Inhibitor
Name:
BDBM50442804
Synonyms:
CHEMBL2440452
Type:
Small organic molecule
Emp. Form.:
C18H23N3O2
Mol. Mass.:
313.3941
SMILES:
O=C(NCC1CCNCC1)c1c2OCCCn2c2ccccc12
Structure:
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