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Found 180 with Last Name = 'monseau' and Initial = 'c'
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433406(CHEMBL2380643)
Affinity DataIC50:  1nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433404(CHEMBL2380641)
Affinity DataIC50:  1nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433405(CHEMBL2380642)
Affinity DataIC50:  2nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499970(CHEMBL3741505)
Affinity DataIC50:  3nMAssay Description:Inhibition of DGAT-1 in human Chang cells assessed as lipid level after 6 hrs in presence of substrate [14C]glycerol by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433411(CHEMBL2380648)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499970(CHEMBL3741505)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human DGAT-1 using 1,2,di(cis-9-octadecenoyl)-sn-glycerol as substrate by Microbeta counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50340438((3-(1H-pyrazol-4-yl)pyrrolidin-1-yl)(3,4-dihydroqu...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433412(CHEMBL2380649)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433403(CHEMBL2380640)
Affinity DataIC50:  5nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433407(CHEMBL2380644)
Affinity DataIC50:  5nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433400(CHEMBL2380637)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433411(CHEMBL2380648)
Affinity DataIC50:  6nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433407(CHEMBL2380644)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50340439((3-(1H-pyrazol-4-yl)pyrrolidin-1-yl)(4,4-dimethyl-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433411(CHEMBL2380648)
Affinity DataIC50:  7nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50340442((3-(1H-pyrazol-4-yl)pyrrolidin-1-yl)(3,4-dihydroqu...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433412(CHEMBL2380649)
Affinity DataIC50:  8nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433408(CHEMBL2380645)
Affinity DataIC50:  8nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50340439((3-(1H-pyrazol-4-yl)pyrrolidin-1-yl)(4,4-dimethyl-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433412(CHEMBL2380649)
Affinity DataIC50:  9nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433408(CHEMBL2380645)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499966(CHEMBL3739742)
Affinity DataIC50:  9nMAssay Description:Inhibition of DGAT-1 in human Chang cells assessed as lipid level after 6 hrs in presence of substrate [14C]glycerol by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50340443((3-(1H-pyrazol-4-yl)pyrrolidin-1-yl)(4-methyl-3,4-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433410(CHEMBL2380647)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433403(CHEMBL2380640)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50340431((4-(1H-imidazol-4-yl)piperidin-1-yl)(3,4-dihydroqu...)
Affinity DataIC50: >10nMAssay Description:Inhibition of human recombinant 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50340432((4-(1H-imidazol-4-yl)piperidin-1-yl)(3-methyl-2H-b...)
Affinity DataIC50: >10nMAssay Description:Inhibition of human recombinant 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433409(CHEMBL2380646)
Affinity DataIC50:  11nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499969(CHEMBL3741095)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human DGAT-1 using 1,2,di(cis-9-octadecenoyl)-sn-glycerol as substrate by Microbeta counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433409(CHEMBL2380646)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50380043(CHEMBL2012612)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant DGAT1 in Chang cells using [14C]-glycerol as substrate assessed as decrease in triglycerides synthesis after 6 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499984(CHEMBL3741333)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human DGAT-1 using 1,2,di(cis-9-octadecenoyl)-sn-glycerol as substrate by Microbeta counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499969(CHEMBL3741095)
Affinity DataIC50:  13nMAssay Description:Inhibition of DGAT-1 in human Chang cells assessed as lipid level after 6 hrs in presence of substrate [14C]glycerol by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433404(CHEMBL2380641)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433400(CHEMBL2380637)
Affinity DataIC50:  15nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499978(CHEMBL3741569)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human DGAT-1 using 1,2,di(cis-9-octadecenoyl)-sn-glycerol as substrate by Microbeta counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433405(CHEMBL2380642)
Affinity DataIC50:  16nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499984(CHEMBL3741333)
Affinity DataIC50:  17nMAssay Description:Inhibition of DGAT-1 in human Chang cells assessed as lipid level after 6 hrs in presence of substrate [14C]glycerol by HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433408(CHEMBL2380645)
Affinity DataIC50:  18nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433402(CHEMBL2380639)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50340440((3-(1H-pyrazol-4-yl)pyrrolidin-1-yl)(2',3'-dihydro...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433405(CHEMBL2380642)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50380043(CHEMBL2012612)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant DGAT1 expressed in baculovirus infected Sf9 cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50340435((4-(1H-pyrazol-4-yl)piperidin-1-yl)(3,4-dihydroqui...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433410(CHEMBL2380647)
Affinity DataIC50:  21nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50340440((3-(1H-pyrazol-4-yl)pyrrolidin-1-yl)(2',3'-dihydro...)
Affinity DataIC50:  21nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433410(CHEMBL2380647)
Affinity DataIC50:  21nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50499966(CHEMBL3739742)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant human DGAT-1 using 1,2,di(cis-9-octadecenoyl)-sn-glycerol as substrate by Microbeta counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50380044(CHEMBL2012614)
Affinity DataIC50:  24nMAssay Description:Inhibition of human recombinant DGAT1 expressed in baculovirus infected Sf9 cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433407(CHEMBL2380644)
Affinity DataIC50:  24nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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