Affinity DataKi: 0.110nMAssay Description:In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.780nMAssay Description:In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.980nMAssay Description:In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.990nMAssay Description:In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Roche Palo Alto
Curated by ChEMBL
Roche Palo Alto
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity determined against alpha-1 adrenergic receptor in rat cortex membranes using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: 1.5nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair