TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.440nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.690nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:50% inhibitory concentration against human carbonic anhydrase II (HCA II) after pre-incubation for 4 min at 37 degree CMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.820nMAssay Description:50% inhibitory concentration against human carbonic anhydrase II (HCA II) after pre-incubation at 3 degree CMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.950nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.34nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.49nMAssay Description:The compound was tested for in vitro binding affinity against human Carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.54nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.58nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.39nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.77nMAssay Description:The compound was tested for in vitro binding affinity against human Carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:The compound was tested for in vitro binding affinity against human Carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity towards IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 6.20nMAssay Description:50% inhibitory concentration against human carbonic anhydrase II (HCA II) after pre-incubation for 4 min at 37 degree CMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 6.80nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:Binding affinity towards IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Inhibition of IL-1 beta converting enzymeMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 9.30nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human Carbonic anhydrase IIMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:50% inhibitory concentration against human carbonic anhydrase II (HCA II) after pre-incubation at 3 degree CMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human carbonic anhydraseMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibitory activity against hepatitis C virus NS3.4A proteaseMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:The compound was tested for in vitro binding affinity against human Carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:The equilibrium dissociation constant of the inhibitor-enzyme complex of human carbonic anhydraseMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Binding affinity towards IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:In vitro binding affinity against human carbonic anhydrase IIChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Binding affinity towards IL-1 beta converting enzyme (ICE)More data for this Ligand-Target Pair