Compile Data Set for Download or QSAR
maximum 50k data
Found 152 with Last Name = 'myles' and Initial = 'd'
TargetEstrogen receptor(Homo sapiens (Human))
Olema Pharmaceuticals

US Patent
LigandPNGBDBM50125052(CHEMBL3623004 | US10130617, Example 1 | US20240043...)
Affinity DataIC50:  0.372nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Olema Pharmaceuticals

US Patent
LigandPNGBDBM50125052(CHEMBL3623004 | US10130617, Example 1 | US20240043...)
Affinity DataIC50:  0.372nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Olema Pharmaceuticals

US Patent
LigandPNGBDBM50125052(CHEMBL3623004 | US10130617, Example 1 | US20240043...)
Affinity DataIC50: <0.640nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Olema Pharmaceuticals

US Patent
LigandPNGBDBM50125052(CHEMBL3623004 | US10130617, Example 1 | US20240043...)
Affinity DataIC50:  1nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Olema Pharmaceuticals

US Patent
LigandPNGBDBM50125054(CHEMBL3623003 | US10130617, Example 2 | WO-2014/19...)
Affinity DataIC50:  1nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Olema Pharmaceuticals

US Patent
LigandPNGBDBM605424(US11672785, Compound C)
Affinity DataIC50:  1.35nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Olema Pharmaceuticals

US Patent
LigandPNGBDBM50503111(CHEMBL4528514 | US11672785, Goodacre Compound 102 ...)
Affinity DataIC50:  1.62nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEstrogen receptor(Homo sapiens (Human))
Olema Pharmaceuticals

US Patent
LigandPNGBDBM605419(US11672785, Example Fulvestrant)
Affinity DataIC50:  2.29nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Olema Pharmaceuticals

US Patent
LigandPNGBDBM605421(US11672785, Compound B)
Affinity DataIC50:  2.69nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Olema Pharmaceuticals

US Patent
LigandPNGBDBM50542087(CHEMBL4635493 | US11672785, Goodacre Compound 107)
Affinity DataIC50:  2.82nMAssay Description:Compounds were screened for their ability to displace a fluorescent labelled tracer ERβ ligand via time resolved fluorescent energy transfer usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50249943(11-O-(Hydrzinocarbonyl)-17-[2-(dimethylamino)ethyl...)
Affinity DataIC50:  5nMAssay Description:Binding affinity to human recombinant HSP90More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50299505(3 9-dihydro-N-desmethyl-N-isopropylerythromycin A ...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344942(CHEMBL532 | E-MYCIN E | ERYTHROMYCIN | ERYTHROMYCI...)
Affinity DataIC50:  39nMAssay Description:Inhibition of human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50299517(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataIC50:  411nMAssay Description:Inhibition of human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344950(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50299517(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataIC50:  4.11E+5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344942(CHEMBL532 | E-MYCIN E | ERYTHROMYCIN | ERYTHROMYCI...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344943((3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-14-ethyl-7...)
Affinity DataEC50:  59nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344944((3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-6-((2S,3R,...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344945((3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-14-ethyl-7...)
Affinity DataEC50:  63nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344946(2-(((2S,3R,4S,6R)-2-((3R,4S,5S,6R,7R,9R,10S,11S,12...)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344947((3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-14-ethyl-7...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344948((3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-14-ethyl-7...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344949(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataEC50:  36nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344950(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataEC50:  17nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344951(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataEC50:  190nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344952((2R,3S,4R,5R,8R,9S,10S,11R,12S)-5-ethyl-11-((2S,3R...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50299505(3 9-dihydro-N-desmethyl-N-isopropylerythromycin A ...)
Affinity DataEC50:  260nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344953((3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-6-((2S,3R,...)
Affinity DataEC50:  350nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344954((3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-14-ethyl-7...)
Affinity DataEC50:  210nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344955((3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-14-ethyl-7...)
Affinity DataEC50:  360nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344956((3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-14-ethyl-7...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50299518(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataEC50:  52nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50299517(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataEC50:  58nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Oryctolagus cuniculus)
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50299502(2-((2R,3S,4R,5R,6S,7R,9R,10R,11S,12S,13R)-2-ethyl-...)
Affinity DataEC50:  660nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50344942(CHEMBL532 | E-MYCIN E | ERYTHROMYCIN | ERYTHROMYCI...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at motilin receptorMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50030841((8S,9S,12S,13R,14S,16R)-19-(2-fluoroethylamino)-13...)
Affinity DataKd:  800nMAssay Description:Binding affinity for human heat shock protein 90 in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50173902((4E,6E)-(15S,16S,19R,21S)-21-(2-Dimethylamino-ethy...)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity for human heat shock protein 90 in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50173907(3H-Imidazole-4-carboxylic acid (E)-(8R,10R,15S,20S...)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity for human heat shock protein 90 in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50173908(1H-Pyrrole-2-carboxylic acid (E)-(8R,10R,15S,20S)-...)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity for human heat shock protein 90 in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50173898(CHEMBL371539 | Geldanamycin derivative)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity for human heat shock protein 90 in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50173909(CHEMBL370149 | N-Methyl-hydrazinecarboxylic acid (...)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity for human heat shock protein 90 in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50173900(CHEMBL371283 | Hydrazinecarboxylic acid (4E,6Z)-(1...)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity for human heat shock protein 90 in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50173901(CHEMBL370404 | Geldanamycin derivative)
Affinity DataKd:  1.80E+4nMAssay Description:Binding affinity for human heat shock protein 90 in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50030868((8S,9S,12S,13R,14S,16R)-19-amino-13-hydroxy-8,14-d...)
Affinity DataKd:  100nMAssay Description:Binding affinity for human heat shock protein 90 in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50173903(CHEMBL197795 | Methyl-carbamic acid (4E,6Z)-(13S,1...)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity for human heat shock protein 90 in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50173906(CHEMBL197741 | Hydrazinecarboxylic acid (4E,6Z)-(1...)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity for human heat shock protein 90 in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50173904((2-Dimethylamino-ethyl)-carbamic acid (4E,6Z)-(13S...)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity for human heat shock protein 90 in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50173905(CHEMBL370418 | Geldanamycin derivative)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity for human heat shock protein 90 in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Kosan Biosciences

Curated by ChEMBL
LigandPNGBDBM50173899(CHEMBL197570 | Carbamoylmethyl-carbamic acid (4E,6...)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity for human heat shock protein 90 in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 152 total ) | Next | Last >>
Jump to: