Affinity DataKi: 0.300nMAssay Description:Binding affinity to human urotensin2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Competitive inhibition of human RIP1 (1 to 375 residues) in presence of increasing ATP by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity to human urotensin2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity to human urotensin2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity to human urotensin2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity to human urotensin2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.01nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity to human urotensin2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity to human urotensin2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.31nMAssay Description:Inhibition of rat EP3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.94nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 12.6nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 12.6nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity to human urotensin2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity to human urotensin2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity to human urotensin2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 15.8nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity to human urotensin2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity to human urotensin2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 19.9nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity to human urotensin2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 25.1nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 79.4nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of human EP3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [125I]hU-2 from human recombinant Urotensin 2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 158nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 398nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair