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Found 72 with Last Name = 'naldini' and Initial = 'a'
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataKi:  13nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50372736(CHEMBL270492)
Affinity DataKi:  20nMAssay Description:Binding affinity to human recombinant Abl by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50354485(CHEMBL412298)
Affinity DataKi:  40nMAssay Description:Binding affinity to human recombinant Abl by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50372741(CHEMBL408966)
Affinity DataKi:  80nMAssay Description:Binding affinity to human recombinant Abl by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343424(1-(2-chloro-2-(4-chlorophenyl)ethyl)-N-(4-fluorobe...)
Affinity DataKi:  80nMAssay Description:Binding affinity to human recombinant Abl by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343424(1-(2-chloro-2-(4-chlorophenyl)ethyl)-N-(4-fluorobe...)
Affinity DataKi:  80nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343427(CHEMBL1775039 | N-Benzyl-1-(2-chloro-2-phenylethyl...)
Affinity DataKi:  90nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50372737(CHEMBL261827)
Affinity DataKi:  100nMAssay Description:Binding affinity to human recombinant Abl by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50372735(CHEMBL429600)
Affinity DataKi:  120nMAssay Description:Binding affinity to human recombinant Abl by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343430(CHEMBL1775036 | N-(3-Chlorophenyl)-1-(2-chloro-2-p...)
Affinity DataKi:  120nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343431(1-(2-Chloro-2-phenylethyl)-6-[(2-morpholin-4-yleth...)
Affinity DataKi:  150nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343430(CHEMBL1775036 | N-(3-Chlorophenyl)-1-(2-chloro-2-p...)
Affinity DataKi:  190nMAssay Description:Inhibition of human recombinant c-Src by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50372738(CHEMBL270286)
Affinity DataKi:  200nMAssay Description:Binding affinity to human recombinant Abl by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50372740(CHEMBL273090)
Affinity DataKi:  200nMAssay Description:Binding affinity to human recombinant Abl by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343431(1-(2-Chloro-2-phenylethyl)-6-[(2-morpholin-4-yleth...)
Affinity DataKi:  210nMAssay Description:Inhibition of human recombinant c-Src by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343421(2-({4-[(2-Phenylethyl)amino]-1-(2-phenylvinyl)-1H-...)
Affinity DataKi:  220nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50142885(Benzyl-[1-(2-chloro-2-phenyl-ethyl)-6-methylsulfan...)
Affinity DataKi:  260nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343429(1-(2-Chloro-2-phenylethyl)-6-[(2-morpholin-4-yleth...)
Affinity DataKi:  270nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343426(1-(2-Chloro-2-phenylethyl)-6-[(2-morpholin-4-yleth...)
Affinity DataKi:  340nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343425(CHEMBL1775041 | N-(3-Chlorophenyl)-1-(2-chloro-2-p...)
Affinity DataKi:  390nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50354486(CHEMBL411043)
Affinity DataKi:  400nMAssay Description:Binding affinity to human recombinant Abl by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50372739(CHEMBL410931)
Affinity DataKi:  440nMAssay Description:Binding affinity to human recombinant Abl by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50145415(1-(2-chloro-2-phenylethyl)-N,N-diethyl-6-(methylth...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataKi:  500nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataKi:  500nMAssay Description:Binding affinity to human recombinant Abl by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343428(1-(2-Chloro-2-phenylethyl)-N-(4-fluorobenzyl)-6-[(...)
Affinity DataKi:  580nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50142882(Butyl-[1-(2-chloro-2-phenyl-ethyl)-6-ethylsulfanyl...)
Affinity DataKi:  600nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343417(1-[2-Chloro-2-(4-chlorophenyl)ethyl]-N-(pyridin-4-...)
Affinity DataKi:  660nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50145425(1-(2-chloro-2-phenylethyl)-6-(ethylthio)-N-propyl-...)
Affinity DataKi:  700nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50142880(1-(2-chloro-2-phenylethyl)-6-(methylthio)-N-phenet...)
Affinity DataKi:  700nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343420(6-(Methylsulfonyl)-1-(2-phenylvinyl)-N-propyl-1H-p...)
Affinity DataKi:  720nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50354487(CHEMBL270958)
Affinity DataKi:  730nMAssay Description:Binding affinity to human recombinant Abl by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343419(CHEMBL1775043 | N-Benzyl-1-(2-chloro-2-phenylethyl...)
Affinity DataKi:  740nMAssay Description:Inhibition of human recombinant c-Src by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343424(1-(2-chloro-2-(4-chlorophenyl)ethyl)-N-(4-fluorobe...)
Affinity DataKi:  800nMAssay Description:Inhibition of human recombinant c-Src by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50183364(1-(2-bromo-2-phenylethyl)-N-propyl-1H-pyrazolo[3,4...)
Affinity DataKi:  900nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343418(1-[2-Chloro-2-(4-chlorophenyl)ethyl]-N-(pyridin-2-...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343428(1-(2-Chloro-2-phenylethyl)-N-(4-fluorobenzyl)-6-[(...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human recombinant c-Src by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50183338(1-(2-bromo-2-phenylethyl)-4-(piperidin-1-yl)-1H-py...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343422(1-[2-Chloro-2-(4-fluorophenyl)ethyl]-N-(pyridin-4-...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50142889(Butyl-[1-(2-chloro-2-phenyl-ethyl)-6-methylsulfany...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343419(CHEMBL1775043 | N-Benzyl-1-(2-chloro-2-phenylethyl...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50354488(CHEMBL272169)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to human recombinant Abl by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343423(1-[2-Chloro-2-(4-fluorophenyl)ethyl]-N-(pyridin-2-...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50142884(1-(2-Chloro-2-phenyl-ethyl)-6-methylsulfanyl-4-pip...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50183355(2-(4-(benzylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-y...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50183347(2-(4-(phenethylamino)-1H-pyrazolo[3,4-d]pyrimidin-...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50183356(CHEMBL203492 | N-benzyl-1-styryl-1H-pyrazolo[3,4-d...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50343421(2-({4-[(2-Phenylethyl)amino]-1-(2-phenylvinyl)-1H-...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human recombinant c-Src by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50183345(1-(2-bromo-2-phenylethyl)-N-(2-ethoxyethyl)-1H-pyr...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50183351(1-(2-bromo-2-phenylethyl)-N-isopropyl-1H-pyrazolo[...)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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