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Found 351 with Last Name = 'nebbioso' and Initial = 'a'
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50236570(CHEMBL4072206)
Affinity DataKi:  2.18E+3nMAssay Description:Uncompetitive inhibition of human N-terminal His6-SUMO-tagged SIRT2 catalytic domain (43 to 356 residues) deacetylase activity expressed in Escherich...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50236570(CHEMBL4072206)
Affinity DataKi:  2.22E+3nMAssay Description:Uncompetitive inhibition of human N-terminal His6-SUMO-tagged SIRT2 catalytic domain (43 to 356 residues) deacetylase activity expressed in Escherich...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  7nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration against maize histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50234055(CHEMBL217494 | N-hydroxy-5-(3,4-dihydro-4-oxo-6-ph...)
Affinity DataIC50:  8nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195608(CHEMBL217791 | N-hydroxy-6-(3,4-dihydro-4-oxo-6-(1...)
Affinity DataIC50:  9nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50234055(CHEMBL217494 | N-hydroxy-5-(3,4-dihydro-4-oxo-6-ph...)
Affinity DataIC50:  10nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50422364(TRAPOXIN B)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against maize histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50134805(6,9-Dibenzyl-12-(6-oxiranyl-6-oxo-hexyl)-decahydro...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against maize histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50234054(6-(6-Oxo-4-phenyl-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  12nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195605(CHEMBL214533 | N-hydroxy-3-(3,4-dihydro-6-phenyl-4...)
Affinity DataIC50:  17nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50234114(6-(4-Benzyl-6-oxo-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  18nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50234114(6-(4-Benzyl-6-oxo-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  18nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50234054(6-(6-Oxo-4-phenyl-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  19nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195609(CHEMBL216147 | N-hydroxy-4-(3,4-dihydro-6-phenyl-4...)
Affinity DataIC50:  23nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195612(CHEMBL384013 | N-hydroxy-4-(3,4-dihydro-4-oxo-6-ph...)
Affinity DataIC50:  27nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  28nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50047966(CHEMBL3314860)
Affinity DataIC50:  30nMT: 2°CAssay Description:Inhibition of human recombinant HDAC6 pre-incubated at room temperature for 15 min before substrate addition by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50047967(CHEMBL3314861)
Affinity DataIC50:  30nMT: 2°CAssay Description:Inhibition of human recombinant HDAC6 pre-incubated at room temperature for 15 min before substrate addition by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full length HDAC6 expressed in insect SF9 cells using fluorogenic ZMAL as substrate after 90 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195612(CHEMBL384013 | N-hydroxy-4-(3,4-dihydro-4-oxo-6-ph...)
Affinity DataIC50:  31nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195614(CHEMBL216064 | N-hydroxy-6-[(3,4-dihydro-4-oxo-6-(...)
Affinity DataIC50:  31nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195614(CHEMBL216064 | N-hydroxy-6-[(3,4-dihydro-4-oxo-6-(...)
Affinity DataIC50:  32nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195609(CHEMBL216147 | N-hydroxy-4-(3,4-dihydro-6-phenyl-4...)
Affinity DataIC50:  34nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195599(CHEMBL214877 | N-hydroxy-3-(3,4-dihydro-4-oxo-6-ph...)
Affinity DataIC50:  37nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195616(CHEMBL387449 | N-hydroxy-7-(3,4-dihydro-4-oxo-6-ph...)
Affinity DataIC50:  38nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  38nMAssay Description:Inhibition of full length His-tagged human recombinant HDAC6 expressed in baculovirus system using fluor de Lys as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 1(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50234054(6-(6-Oxo-4-phenyl-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  39nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195598(CHEMBL216875 | N-hydroxy-5-(3,4-dihydro-4-oxo-6-ph...)
Affinity DataIC50:  40nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50234055(CHEMBL217494 | N-hydroxy-5-(3,4-dihydro-4-oxo-6-ph...)
Affinity DataIC50:  40nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468975(CHEMBL4283913)
Affinity DataIC50:  41nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full length HDAC6 expressed in insect SF9 cells using fluorogenic ZMAL as substrate after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195615(CHEMBL218348 | N-hydroxy-3-(3,4-dihydro-6-benzyl-4...)
Affinity DataIC50:  41nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195602(CHEMBL216834 | N-hydroxy-8-(3,4-dihydro-4-oxo-6-ph...)
Affinity DataIC50:  42nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468978(CHEMBL4291778)
Affinity DataIC50:  42nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full length HDAC6 expressed in insect SF9 cells using fluorogenic ZMAL as substrate after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195615(CHEMBL218348 | N-hydroxy-3-(3,4-dihydro-6-benzyl-4...)
Affinity DataIC50:  42nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195598(CHEMBL216875 | N-hydroxy-5-(3,4-dihydro-4-oxo-6-ph...)
Affinity DataIC50:  46nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195603(CHEMBL217449 | N-hydroxy-6-(3,4-dihydro-4-oxo-6-(1...)
Affinity DataIC50:  47nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195616(CHEMBL387449 | N-hydroxy-7-(3,4-dihydro-4-oxo-6-ph...)
Affinity DataIC50:  48nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  50nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50130725(3-(3-Chloro-4-hydroxy-phenylamino)-4-(2-nitro-phen...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant GSK3beta using GSM as substrate incubated for 30 mins by luminescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration against maize histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195606(CHEMBL214837 | N-hydroxy-6-(3,4-dihydro-4-oxo-6-(1...)
Affinity DataIC50:  52nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195605(CHEMBL214533 | N-hydroxy-3-(3,4-dihydro-6-phenyl-4...)
Affinity DataIC50:  57nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195606(CHEMBL214837 | N-hydroxy-6-(3,4-dihydro-4-oxo-6-(1...)
Affinity DataIC50:  58nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  60nMT: 2°CAssay Description:Inhibition of human recombinant HDAC6 pre-incubated at room temperature for 15 min before substrate addition by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 6(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50047965(CHEMBL3314859)
Affinity DataIC50:  60nMT: 2°CAssay Description:Inhibition of human recombinant HDAC6 pre-incubated at room temperature for 15 min before substrate addition by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468976(CHEMBL4290685)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full length HDAC6 expressed in insect SF9 cells using fluorogenic ZMAL as substrate after 90 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50195599(CHEMBL214877 | N-hydroxy-3-(3,4-dihydro-4-oxo-6-ph...)
Affinity DataIC50:  60nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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