Compile Data Set for Download or QSAR
maximum 50k data
Found 3343 with Last Name = 'nesi' and Initial = 'm'
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(6-[(2-Methoxy-benzyl)-methyl-amino]-hexanoic acid ...)
Affinity DataKi:  0.100nMAssay Description:Inhibition constant determined against Acetylcholinesterase (AChE) receptor.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  0.135nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  0.135nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  0.141nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M4 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  0.141nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M4 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholine O-acetyltransferase(RAT)
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataKi:  0.150nMAssay Description:Inhibition constant determined against Acetylcholinesterase (AChE) receptor.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Universita Di Firenze

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  0.178nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M2 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Universita Di Firenze

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  0.178nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M2 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Universita Di Firenze

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  0.209nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M5 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Universita Di Firenze

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  0.209nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M5 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.224nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1D adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Universita Di Firenze

Curated by ChEMBL
LigandPNGBDBM82423(CAS_132947 | NSC_132947 | TRIPITRAMINE)
Affinity DataKi:  0.270nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
University of Bologna

Curated by PDSP Ki Database
LigandPNGBDBM82559(methoctramine analog 5)
Affinity DataKi:  0.290nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
University of Bologna

Curated by PDSP Ki Database
LigandPNGBDBM82423(CAS_132947 | NSC_132947 | TRIPITRAMINE)
Affinity DataKi:  0.300nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Universita Di Firenze

Curated by ChEMBL
LigandPNGBDBM82423(CAS_132947 | NSC_132947 | TRIPITRAMINE)
Affinity DataKi:  0.302nMAssay Description:Displacement of [3H]N-methylscopolamine chloride from human cloned muscarinic M2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  0.324nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241132(3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9...)
Affinity DataKi:  0.324nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50110300(CHEMBL15056 | N-(4-(3-(piperidin-1-yl)propoxy)phen...)
Affinity DataKi:  0.330nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
University of Bologna

Curated by PDSP Ki Database
LigandPNGBDBM50408535(CHEMBL131865)
Affinity DataKi:  0.370nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
University Of Bras£Lia

Curated by ChEMBL
LigandPNGBDBM50198338(CHEMBL3938038)
Affinity DataKi:  0.389nMAssay Description:Displacement of [3H]prazosin from human alpha1A-adrenoceptor expressed in CHO cell membranes measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.407nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1B adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
University Of Bras£Lia

Curated by ChEMBL
LigandPNGBDBM69602(2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dim...)
Affinity DataKi:  0.427nMAssay Description:Displacement of [3H]prazosin from human cloned Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
University Of Bras£Lia

Curated by ChEMBL
LigandPNGBDBM69602(2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dim...)
Affinity DataKi:  0.427nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1A adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
University of Bologna

Curated by PDSP Ki Database
LigandPNGBDBM50408530(CHEMBL1202003)
Affinity DataKi:  0.440nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50408535(CHEMBL131865)
Affinity DataKi:  0.5nMAssay Description:Binding affinity for rat cortex Muscarinic acetylcholine receptor M1Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50385679(CHEMBL2042405)
Affinity DataKi:  0.501nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM69602(2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dim...)
Affinity DataKi:  0.513nMAssay Description:Displacement of [3H]prazosin from human cloned Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM69602(2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dim...)
Affinity DataKi:  0.513nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1D adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
University of Bologna

Curated by PDSP Ki Database
LigandPNGBDBM50408527(CHEMBL1202004)
Affinity DataKi:  0.560nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
University Of Bras£Lia

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.589nMAssay Description:Binding affinity measured in CHO cells expressing human cloned Alpha-1A adrenergic receptor expressed as pKiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50200566(CHEMBL3902626)
Affinity DataKi:  0.603nMAssay Description:Displacement of [3H]prazosin from human alpha1D-adrenoceptor expressed in CHO cell membranes measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50415153(CHEMBL569307)
Affinity DataKi:  0.692nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  0.75nMAssay Description:Binding affinity against Opioid receptor mu 1 in Guinea pig brain membranes using [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50107696(1,9-di[4-(1-methyl-1,2,3,6-tetrahydro-5-pyridinyl)...)
Affinity DataKi:  0.776nMAssay Description:Displacement of [3H]NMS from human M4 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50385673(CHEMBL2042406)
Affinity DataKi:  0.794nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030223(CHEMBL3354068)
Affinity DataKi:  0.794nMAssay Description:Displacement of [3H]NMS from human M3 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50472355(CHEMBL135974)
Affinity DataKi:  0.832nMAssay Description:Displacement of [3H]8-hydroxy-2-(di-n-propylamino)tetralin from human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030223(CHEMBL3354068)
Affinity DataKi:  0.891nMAssay Description:Displacement of [3H]NMS from human M4 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
University of Bologna

Curated by PDSP Ki Database
LigandPNGBDBM50408525(CHEMBL1202000)
Affinity DataKi:  0.910nMAssay Description:Inhibition of [3H]NMS binding to rat heart Muscarinic acetylcholine receptor M2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030223(CHEMBL3354068)
Affinity DataKi:  0.912nMAssay Description:Displacement of [3H]NMS from human M1 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50026917(8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...)
Affinity DataKi:  0.933nMAssay Description:Displacement of [3H]8-hydroxy-2-(di-n-propylamino)tetralin from human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(RAT)
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50408530(CHEMBL1202003)
Affinity DataKi:  0.950nMAssay Description:Binding affinity for rat cortex Muscarinic acetylcholine receptor M1Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50049563(5-amino-2,4(Bis-4-cyclopropylmethyl-10,17-dihydrox...)
Affinity DataKi:  0.980nMAssay Description:Binding affinity against Opioid receptor mu 1 in Guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030224(CHEMBL3354069)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]NMS from human M1 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50515472(CHEMBL4469822)
Affinity DataKi:  1.10nMAssay Description:Inhibition of equine serum BuChE assessed as dissociation constant for enzyme-substrate-inhibitor complex using butyrylthiocholine iodide as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
University Of Bras£Lia

Curated by ChEMBL
LigandPNGBDBM50201790(CHEMBL3917716)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]prazosin from human alpha1A-adrenoceptor expressed in CHO cell membranes measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
University Of Bras£Lia

Curated by ChEMBL
LigandPNGBDBM50200441(CHEMBL3930616)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]prazosin from human alpha1A-adrenoceptor expressed in CHO cell membranes measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030224(CHEMBL3354069)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]NMS from human M3 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50030224(CHEMBL3354069)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]NMS from human M4 receptor expressed in CHO cells by microplate scintillation counting based radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50515454(CHEMBL4550977)
Affinity DataKi:  1.10nMAssay Description:Inhibition of equine serum BuChE assessed as dissociation constant for enzyme-substrate-inhibitor complex using butyrylthiocholine iodide as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 3343 total ) | Next | Last >>
Jump to: