Found 105 with Last Name = 'njoroge' and Initial = 'm' TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human ERG stably expressed in CHO-K1 cells at -90 mV holding potential by automated Q-patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human ERG stably expressed in CHO-K1 cells at -90 mV holding potential by automated Q-patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human ERG stably expressed in CHO-K1 cells at -90 mV holding potential by automated Q-patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human ERG stably expressed in CHO-K1 cells at -90 mV holding potential by automated Q-patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
Ligand Info
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human ERG stably expressed in CHO-K1 cells at -90 mV holding potential by automated Q-patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of CYP2C8 in human liver microsomes assessed as paclitaxel 6alpha-hydroxylation after 20 mins by LC-MS analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
Ligand Info
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human ERG stably expressed in CHO-K1 cells at -90 mV holding potential by automated Q-patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human ERG expressed in CHO cells assessed as reduction in peak channel current by IonWork patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of CYP2C8 in human liver microsomes assessed as paclitaxel 6alpha-hydroxylation after 20 mins by LC-MS analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
Ligand Info
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
Ligand Info
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human ERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human ERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of human ERG stably expressed in CHO-K1 cells at -90 mV holding potential by automated Q-patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
Ligand Info
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
Ligand Info
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human ERG by patch clamp electrophysiologyMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
Ligand Info
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 860nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
Ligand Info
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 890nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
Ligand Info
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of full length human ERG expressed in CHO cells at -70 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 970nMAssay Description:Inhibition of human ERG stably expressed in CHO-K1 cells at -90 mV holding potential by automated Q-patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of full length human ERG expressed in HEK293 cells assessed as reduction in tail current at holding potential of -70 mV after 6 to 7 mins ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by Q-patch clamp assayMore data for this Ligand-Target Pair
Ligand Info
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human ERG incubated for 4 hrs by fluorescene microplate reader assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human ERG incubated for 4 hrs by fluorescene microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as bufuralol 1'-hydroxylation after 20 mins by LCMS analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as diclofenac 4'-hydroxylation after 20 mins by LCMS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomes assessed as phenacetin O-deethylation after 20 mins by LC-MS analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ERG by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.14E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as diclofenac 4'-hydroxylation after 20 mins by LCMS analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of full length human ERG expressed in CHO cells at -70 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human ERG by patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.46E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as bufuralol 1'-hydroxylation after 20 mins by LCMS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes assessed as paclitaxel 6alpha-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as bufuralol 1'-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human ERG by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town
Curated by ChEMBL
University Of Cape Town
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of full length human ERG expressed in CHO cells at -70 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
