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Found 114 with Last Name = 'oh' and Initial = 'sh'
TargetCholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092532(CHEMBL3586200)
Affinity DataKi:  990nMAssay Description:Inhibition of BChE (unknown origin) by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092540(CHEMBL3586207)
Affinity DataKi:  1.17E+3nMAssay Description:Inhibition of AChE (unknown origin) by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50276756(4,9-bis(3,5-dihydroxyphenoxy)benzofuro[3,2-a]diben...)
Affinity DataKi:  1.30E+3nMAssay Description:Noncompetitive inhibition of human recombinant BACE1 after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50259983(CHEMBL508791 | US10106521, Compound Dieckol | diec...)
Affinity DataKi:  1.50E+3nMAssay Description:Noncompetitive inhibition of human recombinant BACE1 after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092531(CHEMBL3586199)
Affinity DataKi:  2.49E+3nMAssay Description:Inhibition of AChE (unknown origin) by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092529(CHEMBL3586197)
Affinity DataKi:  4.78E+3nMAssay Description:Inhibition of BChE (unknown origin) by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092533(CHEMBL3586201)
Affinity DataKi:  4.88E+3nMAssay Description:Inhibition of BChE (unknown origin) by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFe(3+)-Zn(2+) purple acid phosphatase(Phaseolus vulgaris)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50343030(CHEMBL1771210 | rac-(Dodecanamido(naphthalen-1-yl)...)
Affinity DataKi:  5.00E+3nMpH: 4.9Assay Description:Competitive inhibition of red kidney bean PAP using para-nitrophenol as substrate at pH 4.9 preincubated for 10 mins by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50276826((1-(3',5'-dihydroxyphenoxy)-7-(2'',4'',6-trihydro-...)
Affinity DataKi:  7.20E+3nMAssay Description:Noncompetitive inhibition of human recombinant BACE1 after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50092532(CHEMBL3586200)
Affinity DataKi:  7.97E+3nMAssay Description:Inhibition of AChE (unknown origin) by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50319629(5,8,13,14-Tetraoxa-pentaphene-1,3,6,9,11-pentaol |...)
Affinity DataKi:  8.00E+3nMAssay Description:Noncompetitive inhibition of human recombinant BACE1 after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFe(3+)-Zn(2+) purple acid phosphatase(Phaseolus vulgaris)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50343031(CHEMBL1771211 | rac-(Naphthalen-1-yl(tetradecanami...)
Affinity DataKi:  1.10E+4nMpH: 4.9Assay Description:Competitive inhibition of red kidney bean PAP using para-nitrophenol as substrate at pH 4.9 preincubated for 10 mins by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50319628(CHEMBL1083394 | Triphloroethol A)
Affinity DataKi:  1.21E+4nMAssay Description:Noncompetitive inhibition of human recombinant BACE1 after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM50259982(CHEMBL471187 | US10106521, Compound Eckol | eckol)
Affinity DataKi:  1.39E+4nMAssay Description:Noncompetitive inhibition of human recombinant BACE1 after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pukyong National University

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataKi:  1.40E+4nMAssay Description:Noncompetitive inhibition of human recombinant BACE1 after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFe(3+)-Zn(2+) purple acid phosphatase(Phaseolus vulgaris)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50343032(CHEMBL1771371 | rac-(Naphthalen-1-yl(palmitamido)m...)
Affinity DataKi:  3.10E+4nMpH: 4.9Assay Description:Competitive inhibition of red kidney bean PAP using para-nitrophenol as substrate at pH 4.9 preincubated for 10 mins by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFe(3+)-Zn(2+) purple acid phosphatase(Phaseolus vulgaris)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50343029(CHEMBL1771209 | rac-(Decanamido(naphthalen-1-yl)me...)
Affinity DataKi:  5.70E+4nMpH: 4.9Assay Description:Competitive inhibition of red kidney bean PAP using para-nitrophenol as substrate at pH 4.9 preincubated for 10 mins by UV-visible spectrophotometryMore data for this Ligand-Target Pair
TargetFe(3+)-Zn(2+) purple acid phosphatase(Phaseolus vulgaris)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50343029(CHEMBL1771209 | rac-(Decanamido(naphthalen-1-yl)me...)
Affinity DataKi:  1.02E+5nMpH: 4.9Assay Description:Uncompetitive inhibition of red kidney bean PAP using para-nitrophenol as substrate at pH 4.9 preincubated for 10 mins by UV-visible spectrophotometr...More data for this Ligand-Target Pair
TargetFe(3+)-Zn(2+) purple acid phosphatase(Phaseolus vulgaris)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50343028(CHEMBL1771208 | rac-(Octanamido(naphthalen-1-yl)me...)
Affinity DataKi:  1.95E+5nMpH: 4.9Assay Description:Competitive inhibition of red kidney bean PAP using para-nitrophenol as substrate at pH 4.9 preincubated for 10 mins by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFe(3+)-Zn(2+) purple acid phosphatase(Phaseolus vulgaris)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50343027(CHEMBL1771207 | rac-(Heptanamido(naphthalen-1-yl)m...)
Affinity DataKi:  2.22E+5nMpH: 4.9Assay Description:Competitive inhibition of red kidney bean PAP using para-nitrophenol as substrate at pH 4.9 preincubated for 10 mins by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFe(3+)-Zn(2+) purple acid phosphatase(Phaseolus vulgaris)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50343026(CHEMBL1771206 | rac-(Butyramido(naphthalen-1-yl)me...)
Affinity DataKi:  2.38E+5nMpH: 4.9Assay Description:Competitive inhibition of red kidney bean PAP using para-nitrophenol as substrate at pH 4.9 preincubated for 10 mins by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFe(3+)-Zn(2+) purple acid phosphatase(Phaseolus vulgaris)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50343028(CHEMBL1771208 | rac-(Octanamido(naphthalen-1-yl)me...)
Affinity DataKi:  4.43E+5nMpH: 4.9Assay Description:Uncompetitive inhibition of red kidney bean PAP using para-nitrophenol as substrate at pH 4.9 preincubated for 10 mins by UV-visible spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFe(3+)-Zn(2+) purple acid phosphatase(Phaseolus vulgaris)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50343027(CHEMBL1771207 | rac-(Heptanamido(naphthalen-1-yl)m...)
Affinity DataKi:  4.46E+5nMpH: 4.9Assay Description:Uncompetitive inhibition of red kidney bean PAP using para-nitrophenol as substrate at pH 4.9 preincubated for 10 mins by UV-visible spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFe(3+)-Zn(2+) purple acid phosphatase(Phaseolus vulgaris)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50343026(CHEMBL1771206 | rac-(Butyramido(naphthalen-1-yl)me...)
Affinity DataKi:  6.54E+5nMpH: 4.9Assay Description:Uncompetitive inhibition of red kidney bean PAP using para-nitrophenol as substrate at pH 4.9 preincubated for 10 mins by UV-visible spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50391802((3,4-difluoro-2-(2-fluoro-4-iodophenylamino)phenyl...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50314497(9-(1-ethylpyrrolidin-3-yloxy)-4,6-dihydro-1H-thiop...)
Affinity DataIC50:  13nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase inhibitor()
Bugworks Research

US Patent
LigandPNGBDBM595416(US11590142, Compound 7)
Affinity DataIC50:  18nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50314494(9-(1-ethylpiperidin-3-yloxy)-4,6-dihydro-1H-thiopy...)
Affinity DataIC50:  25nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase inhibitor()
Bugworks Research

US Patent
LigandPNGBDBM595412(US11590142, Compound 2)
Affinity DataIC50:  27nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50314492(9-(piperidin-3-yloxy)-4,6-dihydro-1H-thiopyrano[3,...)
Affinity DataIC50:  28nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50314485(9-(1-(2-hydroxyethyl)piperidin-4-yloxy)-4,6-dihydr...)
Affinity DataIC50:  29nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase inhibitor()
Bugworks Research

US Patent
LigandPNGBDBM595415(US11590142, Compound 5)
Affinity DataIC50:  32nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50314490(9-(1-phenethylpiperidin-4-yloxy)-4,6-dihydro-1H-th...)
Affinity DataIC50:  38nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50314493(9-(1-methylpiperidin-3-yloxy)-4,6-dihydro-1H-thiop...)
Affinity DataIC50:  39nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM27525(N-[3-(morpholin-4-yl)propyl]-8-oxo-9-azatetracyclo...)
Affinity DataIC50:  40nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50314486(9-(1-(2-methoxyethyl)piperidin-4-yloxy)-4,6-dihydr...)
Affinity DataIC50:  40nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50314482(9-(1-propylpiperidin-4-yloxy)-4,6-dihydro-1H-thiop...)
Affinity DataIC50:  42nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50314483(9-(1-pentylpiperidin-4-yloxy)-4,6-dihydro-1H-thiop...)
Affinity DataIC50:  45nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase inhibitor()
Bugworks Research

US Patent
LigandPNGBDBM595413(US11590142, Compound 3)
Affinity DataIC50:  47nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA gyrase inhibitor()
Bugworks Research

US Patent
LigandPNGBDBM595414(US11590142, Compound 4)
Affinity DataIC50:  51nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50314489(9-(1-benzylpiperidin-4-yloxy)-4,6-dihydro-1H-thiop...)
Affinity DataIC50:  53nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50314495(9-(1-propylpiperidin-3-yloxy)-4,6-dihydro-1H-thiop...)
Affinity DataIC50:  56nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase inhibitor()
Bugworks Research

US Patent
LigandPNGBDBM595411(US11590142, Compound 1)
Affinity DataIC50:  67nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50314484(9-(1-isopentylpiperidin-4-yloxy)-4,6-dihydro-1H-th...)
Affinity DataIC50:  71nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50314496(9-(1-methylpyrrolidin-3-yloxy)-4,6-dihydro-1H-thio...)
Affinity DataIC50:  80nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)
Affinity DataIC50:  82nMAssay Description:Inhibition of CDK1/cyclinB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Egyptian Russian University

Curated by ChEMBL
LigandPNGBDBM50560543(CHEMBL4797771)
Affinity DataIC50:  97nMAssay Description:Inhibition of CDK1/cyclinB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jeil Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50314481(9-hydroxy-4,6-dihydro-1H-thiopyrano[3,4-c]quinolin...)
Affinity DataIC50:  99nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Catholic University Of Daegu

Curated by ChEMBL
LigandPNGBDBM50203126(3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...)
Affinity DataIC50:  100nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine as substrate assessed as substrate hydrolysis by spectrophotometric/Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bugworks Research

US Patent
LigandPNGBDBM50462032(CHEBI:3720 | CHEMBL560739 | US11590142, Compound C...)
Affinity DataIC50:  150nMAssay Description:Compounds were solubilised to 100 mM in DMSO before dilution in HBPS to 300 μM. 6-Point concentration-response curves were generated using 3.16-...More data for this Ligand-Target Pair
In DepthDetails US Patent
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