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Found 89 with Last Name = 'pelton' and Initial = 'pd'
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306617((S)-1-fluoro-3-((S)-3-(3-(1,1,2,2-tetrafluoroethox...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50276347((+/-)-1,1,1-trifluoro-3-(2-(3-(1,1,2,2-tetrafluoro...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50276347((+/-)-1,1,1-trifluoro-3-(2-(3-(1,1,2,2-tetrafluoro...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50277885(CHEMBL490868 | Tetrahydroquinline A)
Affinity DataIC50:  39nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306608((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306607((S)-3-((S)-8-(3,5-difluorophenyl)-3-(3-(1,1,2,2-te...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50277959(3-(5-(3-chlorophenyl)-2-(3-(1,1,2,2-te trafluoroet...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306619((S)-1-((S)-3-(3-(1,1,2,2-tetrafluoroethoxy)phenyl)...)
Affinity DataIC50:  88nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306611((S)-1,1,1-trifluoro-3-((S)-3-(3-(trifluoromethoxy)...)
Affinity DataIC50:  94nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50278012(1,1,1-tri fluoro-3-(2-(3-(1,1,2,2-tetrafluoroethox...)
Affinity DataIC50:  96nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306612((S)-3-((S)-3,8-bis(3-(trifluoromethoxy)phenyl)-2H-...)
Affinity DataIC50:  107nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50278011(1,1,1-trifluoro-3-(5-(3-fluorophenyl) -2-(3-(1,1,2...)
Affinity DataIC50:  117nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50277727(3-(2,5-bis(3-(trifluoromethoxy) phenyl)-3,4-dihydr...)
Affinity DataIC50:  125nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50277884((R)-1-((R)-2,5-bis(3-(trifluoromethoxy)phenyl)-3,4...)
Affinity DataIC50:  125nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50278055(1,1,1-trifluoro -3-(5-(3-methoxyphenyl)-2-(3-(1,1,...)
Affinity DataIC50:  126nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306602(3-methyl-1-(3-(3-(1,1,2,2-tetrafluoroethoxy)phenyl...)
Affinity DataIC50:  129nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306612((S)-3-((S)-3,8-bis(3-(trifluoromethoxy)phenyl)-2H-...)
Affinity DataIC50:  133nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50277688(1,1,1-trifluoro-3-(5-(3-(trifluoromethoxy)phenyl)-...)
Affinity DataIC50:  143nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50277688(1,1,1-trifluoro-3-(5-(3-(trifluoromethoxy)phenyl)-...)
Affinity DataIC50:  143nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306618((R)-1-fluoro-3-((S)-3-(3-(1,1,2,2-tetrafluoroethox...)
Affinity DataIC50:  147nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306604(4-propyl-3-(3-(1,1,2,2-tetrafluoroethoxy)phenyl)-8...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306610((S)-3-((S)-8-(3,5-difluorophenyl)-3-(3-(trifluorom...)
Affinity DataIC50:  193nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306613(3-(3-(3-chlorophenyl)-8-(3-(trifluoromethoxy)pheny...)
Affinity DataIC50:  214nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50277459(3-(2-(3-(1,1,2,2-tetrafluoroethoxy)phenyl )-1-(3,3...)
Affinity DataIC50:  235nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306616(3-(3-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-8-(3-(...)
Affinity DataIC50:  271nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306606(1,1,1-trifluoro-3-(8-(3-fluorophenyl)-3-(3-(1,1,2,...)
Affinity DataIC50:  322nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50277812(1-(2,5-bis(3-(trifluoromethoxy) phenyl)-3,4-dihydr...)
Affinity DataIC50:  326nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50277773(1-(2,5-bis(3-(trifluoromethoxy)phenyl)-3,4-dihydro...)
Affinity DataIC50:  331nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306615(1,1,1-trifluoro-3-(8-(3-(trifluoromethoxy)phenyl)-...)
Affinity DataIC50:  360nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50277921(3-(5-(2,3-dichlorophenyl )-2-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306614(3-(3-(3-ethoxyphenyl)-8-(3-(trifluoromethoxy)pheny...)
Affinity DataIC50:  490nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50277460(1,1,1-trifluoro-3-(2-(3-(1,1,2,2-tetrafluoroethoxy...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306603(2-methyl-1-(3-(3-(1,1,2,2-tetrafluoroethoxy)phenyl...)
Affinity DataIC50:  560nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306609((S)-3-((S)-8-(3,5-bis(trifluoromethyl)phenyl)-3-(3...)
Affinity DataIC50:  580nMAssay Description:Inhibition of human cholesteryl ester transfer protein by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50276280(3-(5-(4-chloro-3-ethylphenoxy)-2 -(3-(1,1,2,2-tetr...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50276280(3-(5-(4-chloro-3-ethylphenoxy)-2 -(3-(1,1,2,2-tetr...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50277811(1-(2,5-bis(3-(trifluoromethoxy)phenyl)-3,4-dihydro...)
Affinity DataIC50:  744nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of cholesteryl ester transfer protein in human plasma by [3H]CE HDL assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50277492(1,1,1-trifluoro-3-(5-(pyridin-3-yl)-2-(3-(1,1,2,2-...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50277886(CHEMBL491072 | Tetrahydroquinoline B)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP3A4 tissue isoform in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50306605((S)-1,1,1-trifluoro-3-((S)-3-(3-(1,1,2,2-tetrafluo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP3A4 muscle isoform in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50277557(1,1,1-trifluoro-3-(5-(3-isopropylphenyl)-2-(3-(1,1...)
Affinity DataIC50:  2.77E+5nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50277556(1,1,1-trifluoro-3-(2-(3-(1,1,2,2-tetrafluoroethoxy...)
Affinity DataIC50:  3.17E+5nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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