Affinity DataKi: 0.25nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataKi: 51nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataKi: 57nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 69nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataKi: 171nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataKi: 751nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+3nMAssay Description:Inhibition of DPP-4 (unknown origin) assessed as inhibition of endomorphin-1 degradation after 30 minMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+3nMAssay Description:Inhibition of DPP-4 (unknown origin) assessed as inhibition of endomorphin-2 degradation after 30 minMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataKi: 4.25E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataKi: 7.83E+3nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataKi: 9.17E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataKi: 9.62E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 8.00E+4nMAssay Description:Inhibition of APM (unknown origin) assessed as inhibition of endomorphin-2 degradation after 30 minMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+5nMAssay Description:Inhibition of APM (unknown origin) assessed as inhibition of endomorphin-1 degradation after 30 minMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+5nMAssay Description:Inhibition of DPP-4 (unknown origin) assessed as inhibition of endomorphin-2 degradation after 30 minMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+5nMAssay Description:Inhibition of APM (unknown origin) assessed as inhibition of endomorphin-1 degradation after 30 minMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+5nMAssay Description:Inhibition of DPP-4 (unknown origin) assessed as inhibition of endomorphin-2 degradation after 30 minMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+5nMAssay Description:Inhibition of DPP-4 (unknown origin) assessed as inhibition of endomorphin-1 degradation after 30 minMore data for this Ligand-Target Pair
Affinity DataKi: 2.90E+5nMAssay Description:Inhibition of APM (unknown origin) assessed as inhibition of endomorphin-2 degradation after 30 minMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+5nMAssay Description:Inhibition of APM (unknown origin) assessed as inhibition of endomorphin-2 degradation after 30 minMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+5nMAssay Description:Inhibition of APM (unknown origin) assessed as inhibition of endomorphin-1 degradation after 30 minMore data for this Ligand-Target Pair
Affinity DataKi: 4.20E+5nMAssay Description:Inhibition of DPP-4 (unknown origin) assessed as inhibition of endomorphin-1 degradation after 30 minMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0220nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0350nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Displacement of [3H]DAMGO from Wistar rat mu opioid receptor by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 0.380nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.490nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 0.550nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.560nMAssay Description:Displacement of [3H]DAMGO from Wistar rat mu opioid receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.560nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.610nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair