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Found 7 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50359546'
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataKi:  0.560nMAssay Description:Displacement of [3H]DAMGO from recombinant human mu opioid receptor expressed in CHO cell membranes after 120 mins by liquid scintillation counter an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataIC50:  0.560nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataIC50:  0.560nMAssay Description:Displacement of [3H]DAMGO from Wistar rat mu opioid receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human recombinant MOP expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human recombinant MOR expressed in CHO cells assessed as calcium mobilization by Fluo-4 AM based fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed