TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.410nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.410nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.410nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.440nMAssay Description:Inhibition of [3H]naloxone binding to rat brain membrane with 100 mM NaCl.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.510nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.550nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.660nMAssay Description:Inhibition of [3H]naloxone binding to rat brain membrane with 100 mM NaCl.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.940nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.950nMAssay Description:Inhibition of [3H]naloxone binding to rat brain membrane with 100 mM NaCl.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.980nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of [3H]naloxone binding to rat brain membrane with 100 mM NaCl.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of [3H]naloxone binding to rat brain membrane with 100 mM NaCl.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [3H]naloxone binding to rat brain membrane with 100 mM NaCl.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of [3H]naloxone binding to rat brain membrane with 100 mM NaCl.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of [3H]naloxone binding to rat brain membrane with 100 mM NaCl.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]naloxone binding to rat brain membrane with 100 mM NaCl.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Noncompetitive Iinhibitory activity against human liver DHPR enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against rat striatal synaptosomes Dihydrodipicolinate reductase using 10 uM qBH2 and 50 uM NADH assaysMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of [3H]naloxone binding to rat brain membrane with 100 mM NaCl.More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against rat striatal synaptosomes Dihydrodipicolinate reductase (DHPR)More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Noncompetitive Inhibitory activity against rat striatal synaptosomal DHPR enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:In vitro inhibitory activity against serotonin receptor from rat frontal cortex using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of [3H]naloxone binding to rat brain membrane with 100 mM NaCl.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:In vitro inhibitory activity against dopamine receptor from calf caudate using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of [3H]naloxone binding to rat brain membrane with 100 mM NaCl.More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Binding affinity against Dihydrofolate reductase of rat liverMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of [3H]naloxone binding to rat brain membrane with 100 mM NaCl.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of [3H]naloxone binding to rat brain membrane with 100 mM NaCl.More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against human liver Dihydrodipicolinate reductase (DHPR)More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Binding affinity against Dihydrofolate reductase of rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 145nMAssay Description:In vitro inhibitory activity against dopamine receptor from calf caudate using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Binding affinity against Dihydrofolate reductase of rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against human liver Dihydropteridine reductase using 10 uM qBH2 and 50 uM NADH assaysMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:In vitro inhibitory activity against alpha-2 adrenergic receptor from rat brain minus cerebellum using [3H]clonidine as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 385nMAssay Description:In vitro inhibitory activity against serotonin receptor from whole rat brain using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:In vitro inhibitory activity against alpha-2 adrenergic receptor from rat brain minus cerebellum using [3H]clonidine as radioligandMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibition of [3H]naloxone binding to rat brain membrane with 100 mM NaCl.More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:In vitro inhibitory activity against alpha-2 adrenergic receptor from rat brain minus cerebellum using [3H]clonidine as radioligandMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Binding affinity against Dihydrofolate reductase Inhibitor of chicken liverMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibitory activity against human liver Dihydrodipicolinate reductase (DHPR)More data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Binding affinity against Dihydrofolate reductase of rat liverMore data for this Ligand-Target Pair