Compile Data Set for Download or QSAR
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Found 10 Enz. Inhib. hit(s) with Target = 'Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1' and Ligand = 'BDBM50000788'
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  0.00400nMAssay Description:Concentration for 50% inhibition of [3H]naloxone (1 M) binding to opioid receptor in rat brain membrane was determined in the presence of NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  0.00900nMAssay Description:Concentration for 50% inhibition of [3H]naloxone (1 M) binding to opioid receptor in rat brain membrane was determined in the absence of NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [3H]naloxone binding to opioid receptor in presence of NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [3H]naloxone binding to opioid receptor in presence of NaClMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [3H]naloxone binding to rat brain membrane with 100 mM NaCl.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  44nMAssay Description:Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the presence of NaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  150nMAssay Description:Inhibition of stereospecific [3H]diprenorphine binding to opioid receptors of rat brain homogenates by 50% in the absence of NaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  5.00E+5nMAssay Description:Ability (10 ug/kg) to inhibit binding of [125I]iododexetimide to opioid receptor miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataKd:  154nMAssay Description:Evaluated for Opioid receptor mu 1 affinity against the receptor site model site 1(mu1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed