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Found 217 with Last Name = 'pezzi' and Initial = 'r'
TargetHistone deacetylase 4(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50134803(5,8-Dimethyl-11-(6-oxiranyl-6-oxo-hexyl)-decahydro...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of Histone deacetylase 4 in mammalian cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50297445(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human HDAC6 by fluroimetryChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50134799(6-((5S,8S,11S,13aR)-5,8-Dimethyl-4,7,10,13-tetraox...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of Histone deacetylase 4 in mammalian cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50297444(CHEMBL564876 | N-hydroxy-7,7-di(1H-indol-3-yl)hept...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human HDAC6 by fluroimetryChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration against maize histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50173884((1R,3S,5S,8R)-8-HYDROXY-2-OXABICYCLO[3.3.1]NON-6-E...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration against Histone deacetylase 2 in maizeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  7.20nMAssay Description:Inhibitory activity against maize Histone deacetylase 2 at 1 mMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50422364(TRAPOXIN B)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against maize histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50134805(6,9-Dibenzyl-12-(6-oxiranyl-6-oxo-hexyl)-decahydro...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against maize histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50234054(6-(6-Oxo-4-phenyl-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against Histone deacetylase 2 in maizeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human HDAC11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human HDAC5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50234114(6-(4-Benzyl-6-oxo-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  18nMAssay Description:Inhibitory concentration against Histone deacetylase 2 in maizeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50297446(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human HDAC3 by fluroimetryChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50297446(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human HDAC6 by fluroimetryChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human HDAC10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human HDAC7More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50297445(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human HDAC3 by fluroimetryChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50173893(6-[4-(2-Ethyl-phenyl)-6-oxo-1,6-dihydro-pyrimidin-...)
Affinity DataIC50:  35nMAssay Description:Inhibitory concentration against Histone deacetylase 2 in maizeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50173886(7-(4-Benzyl-6-oxo-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  37nMAssay Description:Inhibitory concentration against Histone deacetylase 2 in maizeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human HDAC9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50173885(3-(4-Benzyl-6-oxo-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  38nMAssay Description:Inhibitory concentration against Histone deacetylase 2 in maizeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  50nMAssay Description:Tested for maize Histone deacetylase 2 inhibitory activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration against Histone deacetylase 2 in maizeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration against maize histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50173895(8-(4-Benzyl-6-oxo-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  61nMAssay Description:Inhibitory concentration against Histone deacetylase 2 in maizeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50278220(CHEMBL471042 | N-hydroxy-3-(4-((4-nitrobenzyloxyim...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50297445(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)
Affinity DataIC50:  83nMAssay Description:Inhibition of human HDAC1 by fluroimetryChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50278221(CHEMBL471043 | methyl 4-((4-(3-(hydroxyamino)-3-ox...)
Affinity DataIC50:  94nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50173888(6-(4-Methyl-6-oxo-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  110nMAssay Description:Inhibitory concentration against Histone deacetylase 2 in maizeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50422363(CHEMBL2311176)
Affinity DataIC50:  110nMAssay Description:Inhibitory concentration against maize histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50278220(CHEMBL471042 | N-hydroxy-3-(4-((4-nitrobenzyloxyim...)
Affinity DataIC50:  124nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50173894(5-(4-Benzyl-6-oxo-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  125nMAssay Description:Inhibitory concentration against Histone deacetylase 2 in maizeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50278344(CHEMBL470843 | N-hydroxy-3-(4-(5-(morpholinomethyl...)
Affinity DataIC50:  127nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50173896(6-(6-Oxo-4-propyl-1,6-dihydro-pyrimidin-2-ylsulfan...)
Affinity DataIC50:  135nMAssay Description:Inhibitory concentration against Histone deacetylase 2 in maizeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50297446(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human HDAC1 by fluroimetryChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50297446(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human HDAC5 by fluroimetryChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50297446(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human HDAC9 by fluroimetryChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50278220(CHEMBL471042 | N-hydroxy-3-(4-((4-nitrobenzyloxyim...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50278344(CHEMBL470843 | N-hydroxy-3-(4-(5-(morpholinomethyl...)
Affinity DataIC50:  175nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50297445(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human HDAC8 by fluroimetryChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50166158((E)-N-Hydroxy-3-[1-methyl-4-(3-naphthalen-1-yl-3-o...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration against maize histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50173891(6-(6-Oxo-1,6-dihydro-pyrimidin-2-ylsulfanyl)-hexan...)
Affinity DataIC50:  213nMAssay Description:Inhibitory concentration against Histone deacetylase 2 in maizeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50297446(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human HDAC7 by fluroimetryChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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