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Found 256 with Last Name = 'planken' and Initial = 'sp'
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Pfizer

WIPO
LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataIC50:  4nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162887(US9056865, A-14)
Affinity DataIC50:  6.40nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162989(US9056865, A-116)
Affinity DataIC50:  6.80nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM163024(US9056865, A-151)
Affinity DataIC50:  7.11nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162966(US9056865, A-93)
Affinity DataIC50:  9.84nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM163026(US9056865, A-153)
Affinity DataIC50:  10.6nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162991(US9056865, A-118)
Affinity DataIC50:  11.1nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM163025(US9056865, A-152)
Affinity DataIC50:  11.4nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM163000(US9056865, A-127)
Affinity DataIC50:  11.5nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM163014(US9056865, A-141)
Affinity DataIC50:  11.6nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162994(US9056865, A-121)
Affinity DataIC50:  11.6nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM163029(US9056865, A-156)
Affinity DataIC50:  12.1nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM163016(US9056865, A-143)
Affinity DataIC50:  12.2nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162971(US9056865, A-98)
Affinity DataIC50:  12.4nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162995(US9056865, A-122)
Affinity DataIC50:  14.7nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM163030(US9056865, A-157)
Affinity DataIC50:  14.8nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162999(US9056865, A-126)
Affinity DataIC50:  15.2nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM163006(US9056865, A-133)
Affinity DataIC50:  16.5nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162990(US9056865, A-117)
Affinity DataIC50:  17nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Pfizer

WIPO
LigandPNGBDBM423450(WO2005113580-Ex-52)
Affinity DataIC50:  17nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162923(US9056865, A-50)
Affinity DataIC50:  17.7nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM163012(US9056865, A-139)
Affinity DataIC50:  17.8nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162881(US9056865, A-8)
Affinity DataIC50:  18.7nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162885(US9056865, A-12)
Affinity DataIC50:  18.8nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162987(US9056865, A-114)
Affinity DataIC50:  19.2nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162976(US9056865, A-103)
Affinity DataIC50:  19.4nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Pfizer

WIPO
LigandPNGBDBM423414(WO2005113580-Ex-08 | cmdc.202100576, 24c)
Affinity DataIC50:  20nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Pfizer

WIPO
LigandPNGBDBM423420(WO2005113580-Ex-16 | cmdc.202100576, 24b)
Affinity DataIC50:  20nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Pfizer

WIPO
LigandPNGBDBM423465(US11753373, Compound A-1-c | WO2006061714, P38.8 |...)
Affinity DataIC50:  20nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM163015(US9056865, A-142)
Affinity DataIC50:  20.4nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162982(US9056865, A-109)
Affinity DataIC50:  20.5nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162889(US9056865, A-16)
Affinity DataIC50:  20.6nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM163022(US9056865, A-149)
Affinity DataIC50:  20.7nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162981(US9056865, A-108)
Affinity DataIC50:  20.8nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162920(US9056865, A-47)
Affinity DataIC50:  21.7nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162988(US9056865, A-115)
Affinity DataIC50:  22nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM163020(US9056865, A-147)
Affinity DataIC50:  22.5nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Pfizer

WIPO
LigandPNGBDBM423418(WO2005113580-Ex-13)
Affinity DataIC50:  23nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162984(US9056865, A-111)
Affinity DataIC50:  23.3nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162907(US9056865, A-34)
Affinity DataIC50:  24.4nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Pfizer

WIPO
LigandPNGBDBM423429(WO2005113580-Ex-27)
Affinity DataIC50:  25nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162916(US9056865, A-43)
Affinity DataIC50:  25.5nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162947(US9056865, A-74)
Affinity DataIC50:  25.5nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162949(US9056865, A-76)
Affinity DataIC50:  25.8nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162964(US9056865, A-91)
Affinity DataIC50:  26.3nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162996(US9056865, A-123)
Affinity DataIC50:  26.7nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162945(US9056865, A-72)
Affinity DataIC50:  28.3nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162962(US9056865, A-89)
Affinity DataIC50:  28.5nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM163027(US9056865, A-154)
Affinity DataIC50:  29.2nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSmoothened homolog(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM162983(US9056865, A-110)
Affinity DataIC50:  29.2nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
In DepthDetails US Patent
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