BindingDB PrimarySearch

Found 404 with Last Name = 'pociecha' and Initial = 'k'

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

Ki: 0.0148nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM433554(US10562853, Compound 74)

Ki: 0.0339nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM433474(US10562853, Compound 1)

Ki: 0.0617nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM433501(US10562853, Compound 18)

Ki: 0.0646nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM433536(US10562853, Compound 59)

Ki: 0.479nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM433515(US10562853, Compound 36)

Ki: 0.525nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50555493(CHEMBL4793515)

Ki: 0.562nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM433519(US10562853, Compound 40)

Ki: 0.617nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)

Ki: 0.813nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM433533(US10562853, Compound 54)

Ki: 1.30nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM433502(US10562853, Compound 19)

Ki: 1.5nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM433532(US10562853, Compound 53)

Ki: 1.90nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50476734(CHEMBL230963)

Ki: 2.20nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM433534(US10562853, Compound 55)

Ki: 2.60nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM433503(US10562853, Compound 21)

Ki: 3.80nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)

Ki: 5nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565201(CHEMBL4782285)

Ki: 8nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM433514(US10562853, Compound 35)

Ki: 14nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565202(CHEMBL4776078)

Ki: 14nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565198(CHEMBL4784726)

Ki: 16nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)

Ki: 18nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)

Ki: 20nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565200(CHEMBL4795248)

Ki: 21nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565199(CHEMBL4787400)

Ki: 21nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM433519(US10562853, Compound 40)

Ki: 23nMAssay Description:Displacement of [3H]-prazosin from alpha1 adrenergic receptor in rat cortex measured after 30 mins by microbeta2 scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565213(CHEMBL4791207)

Ki: 29nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565214(CHEMBL4792591)

Ki: 31nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565221(CHEMBL4795807)

Ki: 34nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50157767(CHEMBL376662 | N-(5-methoxy-1,2,3,4-tetrahydronaph...)

Ki: 35nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor incubated for 60 mins by competitive binding assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM433513(US10562853, Compound 32)

Ki: 35nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565207(CHEMBL4792933)

Ki: 37nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565222(CHEMBL4798559)

Ki: 40nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565223(CHEMBL4798599)

Ki: 43nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565216(CHEMBL4777499)

Ki: 43nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565220(CHEMBL4788452)

Ki: 53nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM433533(US10562853, Compound 54)

Ki: 55nMAssay Description:Displacement of [3H]-prazosin from alpha1 adrenergic receptor in rat cortex measured after 30 mins by microbeta2 scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565197(CHEMBL4779965)

Ki: 61nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565228(CHEMBL4778919)

Ki: 64nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565224(CHEMBL4796041)

Ki: 69nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565227(CHEMBL4779939)

Ki: 70nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565198(CHEMBL4784726)

Ki: 75nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565229(CHEMBL4798767)

Ki: 78nMAssay Description:Binding affinity to 5HT-1A receptor (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565217(CHEMBL4778021)

Ki: 82nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565219(CHEMBL4780228)

Ki: 82nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565215(CHEMBL4798934)

Ki: 82nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565229(CHEMBL4798767)

Ki: 93nMAssay Description:Binding affinity to 5HT7 receptor (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565226(CHEMBL4790694)

Ki: 95nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

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5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565225(CHEMBL4792268)

Ki: 125nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid

Details Article PubMed

Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM433554(US10562853, Compound 74)

Ki: 129nMAssay Description:Displacement of [3H]-prazosin from alpha1 adrenergic receptor in rat cortex measured after 30 mins by microbeta2 scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

PC cid PC sid

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5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL

BDBM50565205(CHEMBL4793191)

Ki: 130nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
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Displayed 1 to 50 (of 404 total ) | Next | Last >>

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Targets 14▿
- 5-hydroxytryptamine receptor 1A 117
- High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A 95
- cAMP-specific 3',5'-cyclic phosphodiesterase 4B 93
- 5-hydroxytryptamine receptor 7 36
- D(2) dopamine receptor 19
- Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor 17
- cAMP-specific 3',5'-cyclic phosphodiesterase 4D 5
- cGMP-specific 3',5'-cyclic phosphodiesterase 4
- Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B 4
- cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A 4
- cGMP-dependent 3',5'-cyclic phosphodiesterase 4
- cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 4
- Cytochrome P450 2D6 1
- Cytochrome P450 3A4 1
- ...
Publications 5▿
- J Med Chem 62: 2750-2771 (2019) 119
- Eur J Med Chem 201: (2020) 90
- Eur J Med Chem 209: (2021) 84
- Eur J Med Chem 146: 381-394 (2018) 59
- Eur J Med Chem 158: 517-533 (2018) 52
Institutions 3▿
- Jagiellonian University Medical College 261
- Palack£ 84
- Jagiellonian University 59
Affinity: 0.015 to 2.0E+5 nM▿
- Ki 129
- IC50 215
- EC50 60
- Affinity ≤ nM
Xtal structures: 7
Docked structures: 0
Catalog Cmpds: 19