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Found 191 with Last Name = 'rangisetty' and Initial = 'jb'
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50143487(CHEMBL353552 | [9-(2,5-Dimethoxy-benzenesulfonyl)-...)
Affinity DataKi:  0.300nMAssay Description:Ability to displace [3H]LSD from human 5-hydroxytryptamine 6 receptor transiently expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50027065((5'alpha)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)e...)
Affinity DataKi:  0.800nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50162877(4-(4-Piperazin-1-yl-naphthalene-1-sulfonyl)-phenyl...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM28583(5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-...)
Affinity DataKi:  1nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50001862((N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50193464(4-(3-benzenesulfonylphenyl)piperazine | CHEMBL2129...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to human 5HT6 receptor in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50143496(4-(4-Dimethylaminomethyl-6-methoxy-1,2,3,4-tetrahy...)
Affinity DataKi:  2nMAssay Description:Ability to displace [3H]LSD from human 5-hydroxytryptamine 6 receptor transiently expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34141(CHEMBL76237 | MS-245)
Affinity DataKi:  2.10nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50130274((9-Benzenesulfonyl-6-methoxy-2,3,4,9-tetrahydro-1H...)
Affinity DataKi:  2.30nMAssay Description:Ability to displace [3H]LSD from human 5-hydroxytryptamine 6 receptor transiently expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50143489(CHEMBL366935 | [9-(4-Iodo-benzenesulfonyl)-6-metho...)
Affinity DataKi:  2.40nMAssay Description:Ability to displace [3H]LSD from human 5-hydroxytryptamine 6 receptor transiently expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50130268(CHEMBL329383 | N-(2,5-Dibromo-3-fluoro-phenyl)-4-m...)
Affinity DataKi:  3nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)
Affinity DataKi:  3.5nMAssay Description:Compound was evaluated for its binding affinity towards human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50162876(1-(4-Benzenesulfonyl-naphthalen-1-yl)-piperazine; ...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50073056(4-Bromo-N-[4-methoxy-3-(4-methyl-piperazin-1-yl)-p...)
Affinity DataKi:  5nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50143492(CHEMBL368746 | [9-(4-Chloro-benzenesulfonyl)-6-met...)
Affinity DataKi:  5nMAssay Description:Ability to displace [3H]LSD from human 5-hydroxytryptamine 6 receptor transiently expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50143493(CHEMBL177107 | [6-Methoxy-9-(naphthalene-2-sulfony...)
Affinity DataKi:  5.10nMAssay Description:Ability to displace [3H]LSD from human 5-hydroxytryptamine 6 receptor transiently expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM112777(NORTRIPTYLINE | US8629135, SW-02)
Affinity DataKi:  6.30nMAssay Description:Compound was evaluated for its binding affinity towards human NET (norepinephrine) transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50193458(4-(4-benzenesulfonylphenyl)piperazine | CHEMBL2115...)
Affinity DataKi:  6.90nMAssay Description:Binding affinity to human 5HT6 receptor in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50143498(CHEMBL425328 | [6-Methoxy-9-(quinoline-8-sulfonyl)...)
Affinity DataKi:  7.60nMAssay Description:Ability to displace [3H]LSD from human 5-hydroxytryptamine 6 receptor transiently expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50091067(2-[2-Methoxy-4-(3-phenyl-propyl)-phenyl]-1-methyl-...)
Affinity DataKi:  8nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2A receptor using [3H]-Ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  9nMAssay Description:Compound was evaluated for its binding affinity towards rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  9nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50162874(1-(3-Phenyl-naphthalen-1-yl)-piperazine; hydrochlo...)
Affinity DataKi:  9.30nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50143494(CHEMBL178691 | [6-Methoxy-9-(toluene-4-sulfonyl)-2...)
Affinity DataKi:  9.40nMAssay Description:Ability to displace [3H]LSD from human 5-hydroxytryptamine 6 receptor transiently expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  10nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50104820(2-[2-Methoxy-4-(3-phenyl-propyl)-phenyl]-ethylamin...)
Affinity DataKi:  12nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34150(4-(3-methyl-1H-indole-1-sulfonyl)aniline, 8 | CHEM...)
Affinity DataKi:  12nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50104815(2-[2-Methoxy-5-(3-phenyl-propyl)-phenyl]-1-methyl-...)
Affinity DataKi:  13nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2A receptor using [3H]-Ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50143500(CHEMBL435524 | [6-Methoxy-9-(naphthalene-1-sulfony...)
Affinity DataKi:  14nMAssay Description:Ability to displace [3H]LSD from human 5-hydroxytryptamine 6 receptor transiently expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50193471(CHEMBL378892 | N,N-dimethyl-2-(1-(phenylsulfonyl)-...)
Affinity DataKi:  15nMAssay Description:Binding affinity to human 5HT6 receptor in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  16nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | CHEMBL2...)
Affinity DataKi:  16nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50193472(CHEMBL378656 | N-(3-(2-aminoethyl)-4-methoxyphenyl...)
Affinity DataKi:  17nMAssay Description:Binding affinity to human 5HT6 receptor in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50106261(CHEMBL316881 | [3-(2-Dimethylamino-ethyl)-5-methox...)
Affinity DataKi:  18nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50104820(2-[2-Methoxy-4-(3-phenyl-propyl)-phenyl]-ethylamin...)
Affinity DataKi:  18nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2A receptor using [3H]-Ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50104828(2-[2-Methoxy-4-(5-phenyl-pentyl)-phenyl]-ethylamin...)
Affinity DataKi:  18nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50104828(2-[2-Methoxy-4-(5-phenyl-pentyl)-phenyl]-ethylamin...)
Affinity DataKi:  19nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50104815(2-[2-Methoxy-5-(3-phenyl-propyl)-phenyl]-1-methyl-...)
Affinity DataKi:  19nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085970(CHEMBL7318 | [2-(5-Methoxy-2-phenyl-1H-indol-3-yl)...)
Affinity DataKi:  20nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50104818(2-[2-Methoxy-5-(3-phenyl-propyl)-phenyl]-ethylamin...)
Affinity DataKi:  20nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2A receptor using [3H]-Ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50085970(CHEMBL7318 | [2-(5-Methoxy-2-phenyl-1H-indol-3-yl)...)
Affinity DataKi:  20nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50193463(CHEMBL212063 | N-(3-(2-aminoethyl)phenyl)benzenesu...)
Affinity DataKi:  21nMAssay Description:Binding affinity to human 5HT6 receptor in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50162880(1-(3-Ethyl-naphthalen-1-yl)-piperazine; hydrochlor...)
Affinity DataKi:  21nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50027065((5'alpha)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)e...)
Affinity DataKi:  22nMAssay Description:Compound was evaluated for its binding affinity towards human 5-hydroxytryptamine 5A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50104814(2-(4-Benzyl-2-methoxy-phenyl)-ethylamine | CHEMBL1...)
Affinity DataKi:  23nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2A receptor using [3H]-Ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  23nMAssay Description:Compound was evaluated for its binding affinity towards rat r5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50452060(CHEMBL1189868)
Affinity DataKi:  29nMAssay Description:Ability to displace [3H]LSD from human 5-hydroxytryptamine 6 receptor transiently expressed in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014990(1-(2,5-dimethoxy-4-(3-phenylpropyl)phenyl)propan-2...)
Affinity DataKi:  30nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2A receptor using [3H]-Ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50104818(2-[2-Methoxy-5-(3-phenyl-propyl)-phenyl]-ethylamin...)
Affinity DataKi:  30nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005257((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataKi:  32nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 2A receptor using [3H]-Ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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