Affinity DataKi: <0.0100nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from human BCL-2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant by fluo...More data for this Ligand-Target Pair
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Inhibition of SAH hydrolase (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Displacement of [I125]CGRP from human CGRP receptor in SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.0128nMAssay Description:Displacement of [I125]CGRP from human CGRP receptor in SK-N-MC cellsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Displacement of [I125]CGRP from human CGRP receptor in SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cell membrane after 2 hrsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.550nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cell membrane after 2 hrsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.550nMAssay Description:Displacement of [I125]CGRP from human CGRP receptor in SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.550nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cell membrane after 2 hrsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.650nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cell membrane after 2 hrsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 0.650nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cell membrane after 2 hrsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 90 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Competitive binding assay using cannabinoid receptors.More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cell membrane after 2 hrsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affiliated Hospital Of Guangdong Medical University
Curated by ChEMBL
Affinity DataKi: <3nMAssay Description:Inhibition of EZH2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 90 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 90 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 90 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 90 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 7.20nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cell membrane after 2 hrsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 7.30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 90 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 90 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 90 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cell membrane after 2 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 90 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 90 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 90 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 90 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 90 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cell membrane after 2 hrsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Bristol-Myers Squibb Research & Development
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cell membrane after 2 hrsMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of [3H]-DAMGO from human MOR expressed in CHO-K1 cell membranes incubated for 90 mins measured by MicroBeta scintillation counter methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 34nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Jiangsu Ocean University
Curated by ChEMBL
Jiangsu Ocean University
Curated by ChEMBL
Affinity DataKi: 34nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes by microbeta scintillation counting methodMore data for this Ligand-Target Pair