Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.00145nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0427nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0525nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0537nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0646nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0741nMAssay Description:Antagonistic activity at human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.102nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.107nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.141nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.195nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.234nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of NIK (unknown origin) after 1 to 2 hrs by ADP-FP assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.339nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.339nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of NIK (unknown origin) after 1 to 2 hrs by ADP-FP assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.470nMAssay Description:Inhibition of NIK (unknown origin) after 1 to 2 hrs by ADP-FP assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.759nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Inhibition of NIK (unknown origin) after 1 to 2 hrs by ADP-FP assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.813nMAssay Description:Antagonistic activity at human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita Degli Studi Di Bari
Curated by ChEMBL
Universita Degli Studi Di Bari
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Inhibition of NIK (unknown origin) after 1 to 2 hrs by ADP-FP assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of Alexa647-labeled JQ1 derivative from wild type BRD4 tandem domain (44 to 460 residues) (unknown origin) incubated for 1 hr by fluores...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of NIK (unknown origin) after 1 to 2 hrs by ADP-FP assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita Degli Studi Di Bari
Curated by ChEMBL
Universita Degli Studi Di Bari
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of fluorescently labeled VER51001 binding to full length human HSP90beta after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of fluorescently labeled VER51001 binding to full length human HSP90beta after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of fluorescently labeled VER51001 binding to full length human HSP90beta after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Universita Degli Studi Di Bari
Curated by ChEMBL
Universita Degli Studi Di Bari
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair