TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Binding affinity to PLK1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 76nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 95nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataKi: 129nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate after 120 mins in presence of [gamma-33P]-ATP by filtration methodMore data for this Ligand-Target Pair
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 273nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 540nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetDeath-associated protein kinase 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataKi: 581nMAssay Description:Inhibition of human DAPK1 (1 to 363 residues) using KKLNRTLSFAEPG as substrate after 120 mins [gamma-33P]-ATP by filtration methodMore data for this Ligand-Target Pair
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 650nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 706nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.43E+3nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 2.01E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 2.09E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 2.17E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 2.27E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 4.58E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.53E+4nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 1.53E+4nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of CAMK2b (unknown origin)More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 0.160nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PAK1 (unknown origin)More data for this Ligand-Target Pair
TargetHomeodomain-interacting protein kinase 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 0.367nMAssay Description:Inhibition of HIPK1 (unknown origin)More data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 0.370nMAssay Description:Inhibition of PKCalpha (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:Inhibition of PDGFRalpha (unknown origin)More data for this Ligand-Target Pair
TargetMisshapen-like kinase 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 0.470nMAssay Description:Inhibition of MINK1 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 0.473nMAssay Description:Inhibition of LYN (unknown origin)More data for this Ligand-Target Pair
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 0.490nMAssay Description:Inhibition of PHKg2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human AXL using EAIYAAPFAKKK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: <0.5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human AXL (473 to end amino acids) expressed by baculovirus in Sf9 cells using axltide substrate and ...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 0.640nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 0.720nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin)More data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 0.860nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.940nMAssay Description:Inhibition of N-terminal His-tagged recombinant human AXL (473 to end amino acids) expressed by baculovirus in Sf9 cells using axltide substrate and ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of LCK (unknown origin) after 120 mins in presence of 33P-ATPMore data for this Ligand-Target Pair
TargetInsulin receptor(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human InsR expressed in mouse IGF1R knockout MEF cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]-diprenorphine binding to kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human IGF1R expressed in mouse IGF1R knockout MEF cellsMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of wild type ALK (unknown origin)More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ALK G1202R mutant (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kist)
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
University Of Science And Technology (Ust)
Curated by ChEMBL
University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sogang University
Curated by ChEMBL
Sogang University
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Displacement of [3H]Nisoxetine from human recombinant NET over-expressed in dog MDCK cellsMore data for this Ligand-Target Pair