Compile Data Set for Download or QSAR
maximum 50k data
Found 637 with Last Name = 'roh' and Initial = 'ej'
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50355500(CHEMBL1908394 | US9695172, GSK461364)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to PLK1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50215404(CHEMBL227235 | [3-(2-iodo-6-methylaminopurin-9-yl)...)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50121987(CHEMBL153254 | [3-(2-Chloro-6-methylamino-purin-9-...)
Affinity DataKi:  76nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50215406((1'R,2'S,4'S,5'S)-4-(2-ethynyl-6-methylaminopurin-...)
Affinity DataKi:  95nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50520846(CHEMBL4461911)
Affinity DataKi:  129nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate after 120 mins in presence of [gamma-33P]-ATP by filtration methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50215400((1'R,2'S,4'R,5'S)-phosphoric acid mono-[4-(6-methy...)
Affinity DataKi:  273nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50215402((1'R,2'S,4'R,5'S)-phosphoric acid mono-[4-(2-cyano...)
Affinity DataKi:  540nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50520846(CHEMBL4461911)
Affinity DataKi:  581nMAssay Description:Inhibition of human DAPK1 (1 to 363 residues) using KKLNRTLSFAEPG as substrate after 120 mins [gamma-33P]-ATP by filtration methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50215403((1'R,2'S,4'R,5'S)-phosphoric acid mono-[4-(2-carba...)
Affinity DataKi:  650nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50215401((1'R,2'S,4'S,5'S)-phosphoric acid mono-[1-hydroxym...)
Affinity DataKi:  706nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50215405((1'R,2'S,4'R,5'S)-6-methylamino-9-(4-phosphonooxy-...)
Affinity DataKi:  1.43E+3nMAssay Description:Displacement of [3H]MRS2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50275734(CHEMBL108801 | ethyl 4-ethyl-5-(ethylthiocarbonyl)...)
Affinity DataKi:  2.01E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50275838(CHEMBL111239 | ethyl 4-ethyl-5-(ethylthiocarbonyl)...)
Affinity DataKi:  2.09E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50275836(3-ethylthio-5-ethyl-2-methyl-4-propyl-6-(3-chlorop...)
Affinity DataKi:  2.17E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50025067(CHEMBL105764)
Affinity DataKi:  2.27E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50275899(3,5-diethyl-2-methyl-4-ethyl-6-phenyl-1,4-(+)-dihy...)
Affinity DataKi:  4.58E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50275730(CHEMBL108374 | diethyl 4-(dimethoxymethyl)-2-methy...)
Affinity DataKi:  1.53E+4nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50275837(CHEMBL110635 | ethyl 4,6-diethyl-5-(ethylthiocarbo...)
Affinity DataKi:  1.53E+4nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of CAMK2b (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of PAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHomeodomain-interacting protein kinase 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50400734(CHEMBL1591531)
Affinity DataIC50:  0.367nMAssay Description:Inhibition of HIPK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of PKCalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of PDGFRalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMisshapen-like kinase 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of MINK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.473nMAssay Description:Inhibition of LYN (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphorylase b kinase gamma catalytic chain, liver/testis isoform(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of PHKg2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human AXL using EAIYAAPFAKKK as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506637(CHEMBL4476226)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of N-terminal His-tagged recombinant human AXL (473 to end amino acids) expressed by baculovirus in Sf9 cells using axltide substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.640nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.720nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.860nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50506648(CHEMBL4445940)
Affinity DataIC50:  0.940nMAssay Description:Inhibition of N-terminal His-tagged recombinant human AXL (473 to end amino acids) expressed by baculovirus in Sf9 cells using axltide substrate and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1nMAssay Description:Inhibition of LCK (unknown origin) after 120 mins in presence of 33P-ATPMore data for this Ligand-Target Pair
TargetInsulin receptor(Homo sapiens (Human))
University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50587680(CHEMBL5182271)
Affinity DataIC50:  1nMAssay Description:Inhibition of human InsR expressed in mouse IGF1R knockout MEF cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50358430(CHEMBL1614725)
Affinity DataIC50:  1nMAssay Description:Inhibition of [3H]-diprenorphine binding to kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50587680(CHEMBL5182271)
Affinity DataIC50:  1nMAssay Description:Inhibition of human IGF1R expressed in mouse IGF1R knockout MEF cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50587677(CHEMBL5173501)
Affinity DataIC50:  1nMAssay Description:Inhibition of wild type ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50587677(CHEMBL5173501)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50587677(CHEMBL5173501)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of ALK G1202R mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50587681(CHEMBL5176650)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50587675(CHEMBL4303523)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50587675(CHEMBL4303523)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sogang University

Curated by ChEMBL
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [3H]Nisoxetine from human recombinant NET over-expressed in dog MDCK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Displayed 1 to 50 (of 637 total ) | Next | Last >>
Jump to: