TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured for 10 mins by fluor...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataKi: 420nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured for 10 mins by fluor...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Mixed type inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Double reciprocal plo...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Mixed non-competitive inhibition of full length recombinant human PTP1B assessed as enzyme-substrate-inhibitor complex using pNPP as substrate by dou...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Noncompetitive inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Double reciprocal...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Competitive inhibition of full length recombinant human PTP1B assessed as enzyme-inhibitor complex using pNPP as substrate by double reciprocal plot ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Competitive inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Double reciprocal pl...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Mixed non-competitive inhibition of full length recombinant human PTP1B assessed as enzyme-substrate-inhibitor complex using pNPP as substrate by dou...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Mixed type inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Double reciprocal plo...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataKi: 2.12E+3nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured for 10 mins by fluor...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataKi: 2.18E+3nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured for 10 mins by fluor...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:Mixed type inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Double reciprocal plo...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:Mixed non-competitive inhibition of full length recombinant human PTP1B assessed as enzyme-substrate-inhibitor complex using pNPP as substrate by dou...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 4.40E+3nMAssay Description:Competitive inhibition of full length recombinant human PTP1B assessed as enzyme-inhibitor complex using pNPP as substrate by double reciprocal plot ...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataKi: 4.70E+3nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured for 10 mins by fluor...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataKi: 5.52E+3nMAssay Description:Competitive inhibition of post-glutamyl peptide hydrolyzing activity of human 20S proteasome using Cbz-Leu-Leu-Glu-AMC as substrate measured for 10 m...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataKi: 8.59E+3nMAssay Description:Competitive inhibition of post-glutamyl peptide hydrolyzing activity of human 20S proteasome using Cbz-Leu-Leu-Glu-AMC as substrate measured for 10 m...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 9.90E+3nMAssay Description:Competitive inhibition of full length recombinant human PTP1B assessed as enzyme-inhibitor complex using pNPP as substrate by double reciprocal plot ...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataKi: 1.03E+4nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured for 10 mins by fluor...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataKi: 1.10E+4nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured for 10 mins by fluor...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataKi: 2.21E+4nMAssay Description:Competitive inhibition of trypsin-like activity of human 20S proteasome using Boc-Leu-Arg-Arg-AMC as substrate measured for 10 mins by fluorescence a...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataKi: 3.13E+4nMAssay Description:Competitive inhibition of post-glutamyl peptide hydrolyzing activity of human 20S proteasome using Cbz-Leu-Leu-Glu-AMC as substrate measured for 10 m...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human recombinant LMW-PTP IF1 expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant LMW-PTP IF1 expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human recombinant LMW-PTP IF1 expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of full length recombinant human PTP1B using pNPP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair