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Found 626 with Last Name = 'sakamoto' and Initial = 'h'
TargetCoagulation factor X(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50372526(CHEMBL261646)
Affinity DataKi:  15nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50344644(8-(2-(diethylamino)ethoxy)-3-ethoxy-6,6-dimethylbe...)
Affinity DataKi:  170nMAssay Description:Competitive inhibition of ALK phosphorylation by Lineweaver-Burk plot analysisChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50270656(2-(1-(3-(6-chloronaphthalen-2-ylsulfonyl)propanoyl...)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50372526(CHEMBL261646)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50270656(2-(1-(3-(6-chloronaphthalen-2-ylsulfonyl)propanoyl...)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of tPA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50270656(2-(1-(3-(6-chloronaphthalen-2-ylsulfonyl)propanoyl...)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50372526(CHEMBL261646)
Affinity DataKi:  6.70E+4nMAssay Description:Inhibition of human tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50372526(CHEMBL261646)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178978(US9126931, 277)
Affinity DataIC50:  0.168nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179072(US9126931, 822)
Affinity DataIC50:  0.300nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179073(US9126931, 823)
Affinity DataIC50:  0.300nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179071(US9126931, 796)
Affinity DataIC50:  0.300nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179026(US9126931, 543)
Affinity DataIC50:  0.320nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178992(US9126931, 338)
Affinity DataIC50:  0.320nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM99943(US8501750, 56)
Affinity DataIC50:  0.340nMAssay Description:Binding assay using human AT1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179002(US9126931, 403)
Affinity DataIC50:  0.391nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178997(US9126931, 359)
Affinity DataIC50:  0.400nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179069(US9126931, 786)
Affinity DataIC50:  0.400nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179033(US9126931, 601)
Affinity DataIC50:  0.456nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179083(US9126931, 882)
Affinity DataIC50:  0.494nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179000(US9126931, 380)
Affinity DataIC50:  0.530nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178993(US9126931, 340)
Affinity DataIC50:  0.580nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179019(US9126931, 486)
Affinity DataIC50:  0.590nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179076(US9126931, 832)
Affinity DataIC50:  0.600nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179075(US9126931, 829)
Affinity DataIC50:  0.700nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179030(US9126931, 579)
Affinity DataIC50:  0.770nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM99950(US8501750, 83)
Affinity DataIC50:  0.770nMAssay Description:Binding assay using human AT1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178985(US9126931, 304)
Affinity DataIC50:  0.810nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179079(US9126931, 849)
Affinity DataIC50:  0.813nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179009(US9126931, 429)
Affinity DataIC50:  0.830nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178963(US9126931, 177)
Affinity DataIC50:  0.840nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179027(US9126931, 546)
Affinity DataIC50:  0.860nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178988(US9126931, 319)
Affinity DataIC50:  0.881nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179028(US9126931, 550)
Affinity DataIC50:  0.900nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178980(US9126931, 286)
Affinity DataIC50:  0.952nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178939(US9126931, 109)
Affinity DataIC50:  0.981nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178970(US9126931, 226)
Affinity DataIC50:  0.991nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178987(US9126931, 314)
Affinity DataIC50:  0.996nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM99949(US8501750, 76)
Affinity DataIC50:  1nMAssay Description:Binding assay using human AT1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM99946(US8501750, 60)
Affinity DataIC50:  1nMAssay Description:Binding assay using human AT1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM99952(US8501750, 105)
Affinity DataIC50:  1nMAssay Description:Binding assay using human AT1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178995(US9126931, 355)
Affinity DataIC50:  1.09nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50362779(CHEMBL1940181 | US9126931, 346)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of ALK using Bio-Gastrintide as substrate by TR-FRET assay in presence of 30 uM of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50362778(CHEMBL1940182)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of ALK using Bio-Gastrintide as substrate by TR-FRET assay in presence of 30 uM of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM99947(US8501750, 63)
Affinity DataIC50:  1.10nMAssay Description:Binding assay using human AT1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM99953(US8501750, 107)
Affinity DataIC50:  1.10nMAssay Description:Binding assay using human AT1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM178981(US9126931, 290)
Affinity DataIC50:  1.13nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM179008(US9126931, 426)
Affinity DataIC50:  1.17nMAssay Description:ALK-inhibiting activity was measured by following an activity of inhibiting phosphorylation by biotinylated peptide (EGPWLEEEEEAYGWMDF). For the dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM99951(US8501750, 99)
Affinity DataIC50:  1.20nMAssay Description:Binding assay using human AT1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM99961(US8501750, 131)
Affinity DataIC50:  1.20nMAssay Description:Binding assay using human AT1.More data for this Ligand-Target Pair
In DepthDetails US Patent
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