Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -48.6kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.9kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
Affinity DataKi: 6nM ΔG°: -46.9kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor after 45 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 12nM ΔG°: -45.2kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
Affinity DataKi: 15nM ΔG°: -44.7kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
Affinity DataKi: 18nM ΔG°: -44.2kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
Affinity DataKi: 23nM ΔG°: -43.6kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
Affinity DataKi: 25nM ΔG°: -43.4kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
Affinity DataKi: 34nM ΔG°: -42.6kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
Affinity DataKi: 41nM ΔG°: -42.2kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
Affinity DataKi: 143nM ΔG°: -39.1kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
Affinity DataKi: 156nM ΔG°: -38.9kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
Affinity DataKi: 157nM ΔG°: -38.8kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
Affinity DataKi: 190nM ΔG°: -38.4kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 203nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 253nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in Sf9 cell membranes co-expressing Galphai2 and Gbeta1gamma2 after 60 mins by liquid ...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 378nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 408nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 431nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 524nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 703nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in Sf9 cell membranes co-expressing Galphai2 and Gbeta1gamma2 after 60 mins by liquid ...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 790nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 834nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Mus musculus (mouse))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 854nMAssay Description:Displacement of [3H]histamine from mouse H4 receptor expressed in HEK293 cell membranes co-expressing Galphai2 and Gbeta1gamma2 after 1 hr by liquid ...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nM ΔG°: -34.2kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 1.14E+3nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in Sf9 cell membranes co-expressing Galphai2 and Gbeta1gamma2 after 60 mins by liquid ...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 1.19E+3nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 1.26E+3nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 1.47E+3nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 1.75E+3nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 1.78E+3nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in Sf9 cell membranes co-expressing Galphai2 and Gbeta1gamma2 after 60 mins by liquid ...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 1.79E+3nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
Affinity DataKi: 1.81E+3nM ΔG°: -32.8kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 2.23E+3nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in Sf9 cell membranes co-expressing Galphai2 and Gbeta1gamma2 after 60 mins by liquid ...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 2.36E+3nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 2.39E+3nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 2.45E+3nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in Sf9 cell membranes co-expressing Galphai2 and Gbeta1gamma2 after 60 mins by liquid ...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 2.53E+3nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in Sf9 cell membranes co-expressing Galphai2 and Gbeta1gamma2 after 60 mins by liquid ...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 2.57E+3nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in Sf9 cell membranes co-expressing Galphai2 and Gbeta1gamma2 after 60 mins by liquid ...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 2.64E+3nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in Sf9 cell membranes co-expressing Galphai2 and Gbeta1gamma2 after 60 mins by liquid ...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 3.52E+3nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in Sf9 cell membranes co-expressing Galphai2 and Gbeta1gamma2 after 60 mins by liquid ...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 3.79E+3nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in Sf9 cell membranes co-expressing Galphai2 and Gbeta1gamma2 after 60 mins by liquid ...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 4.21E+3nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in Sf9 cell membranes co-expressing Galphai2 and Gbeta1gamma2 after 60 mins by liquid ...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 4.24E+3nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...More data for this Ligand-Target Pair
Affinity DataKi: 4.47E+3nM ΔG°: -30.5kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair