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Found 174 with Last Name = 'schnur' and Initial = 'rc'
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016653(CHEMBL19187 | N-Benzyl-4-chloro-2-(2,5-dioxo-imida...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016634(5-(5-Chloro-2-methanesulfonyl-phenyl)-imidazolidin...)
Affinity DataIC50:  50nMAssay Description:Compound was evaluated for inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016646(5-[5-Chloro-2-(pentane-1-sulfonyl)-phenyl]-imidazo...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016629(4-Chloro-2-(2,5-dioxo-imidazolidin-4-yl)-N-(3-phen...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226988(CHEMBL81536)
Affinity DataIC50: <100nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductase; value ranges from 10E-5 to 10E-6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226984(CHEMBL77679)
Affinity DataIC50: <100nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226987(CHEMBL78819)
Affinity DataIC50: <100nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227014(CHEMBL432927)
Affinity DataIC50: <100nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226983(CHEMBL79461)
Affinity DataIC50: <100nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226991(CHEMBL419474)
Affinity DataIC50: <100nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226985(CHEMBL309288)
Affinity DataIC50: <100nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022424(6',8'-dichlorospiro[tetrahydro-1H-imidazole-4,4'-(...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022470(6',8'-dichlorospiro[tetrahydro-1H-imidazole-4,4'-(...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022480(CHEMBL78963 | c6-chlorospiro[3,4-dihydro-2H-chrome...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022415(6-chloro-(4'S)-spiro[3,4-dihydro-2H-chromene-4,5'-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022499(7-methoxyspiro[3,4-dihydro-2H-benzo[h]chromene-4,4...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016640(4-Chloro-2-(2,5-dioxo-imidazolidin-4-yl)-N-methyl-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016642(4-Chloro-2-(2,5-dioxo-imidazolidin-4-yl)-benzenesu...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016644(5-(5-Chloro-2-ethanesulfonyl-phenyl)-imidazolidine...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016633(4-Chloro-2-(2,5-dioxo-imidazolidin-4-yl)-N-pentyl-...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016652(5-{5-Chloro-2-[2-(4-chloro-phenyl)-ethanesulfonyl]...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016630(5-[5-Chloro-2-(hexane-1-sulfonyl)-phenyl]-imidazol...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016632(4-Chloro-2-(2,5-dioxo-imidazolidin-4-yl)-N-(4-fluo...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016631(5-(5-Chloro-2-methanesulfinyl-phenyl)-imidazolidin...)
Affinity DataIC50:  250nMAssay Description:Compound was evaluated for inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016638(5-[5-Chloro-2-(propane-1-sulfonyl)-phenyl]-imidazo...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016645(5-[5-Chloro-2-(4-chloro-phenylmethanesulfonyl)-phe...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016637(5-(5-Chloro-2-methanesulfonyl-3-methyl-phenyl)-imi...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016655(5-[5-Chloro-2-(propane-2-sulfonyl)-phenyl]-imidazo...)
Affinity DataIC50:  380nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016635(5-[5-Chloro-2-(4-chloro-phenylmethanesulfinyl)-phe...)
Affinity DataIC50:  470nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibitory activity towards human placenta aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity of the compound was determined against human placental aldose reductase (HPAR) with glyceraldehyde as substrateMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016641(5-(5-Chloro-2-methanesulfonyl-3-trifluoromethyl-ph...)
Affinity DataIC50:  580nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016647(4-Chloro-2-(2,5-dioxo-imidazolidin-4-yl)-N-propyl-...)
Affinity DataIC50:  580nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016656(5-(3,5-Dichloro-2-methanesulfonyl-phenyl)-imidazol...)
Affinity DataIC50:  610nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016628(5-(5-Fluoro-2-methanesulfonyl-phenyl)-imidazolidin...)
Affinity DataIC50:  610nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016649(5-(5-Chloro-2-methylsulfanyl-phenyl)-imidazolidine...)
Affinity DataIC50:  620nMAssay Description:Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50016654(CHEMBL19064 | N-Butyl-4-chloro-2-(2,5-dioxo-imidaz...)
Affinity DataIC50:  700nMAssay Description:Compound was evaluated for inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022401(8-phenylspiro[3,4-dihydro-2H-chromene-4,4'-(tetrah...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory activity towards partially purified calf lens aldose reductase; value ranges from 10E-6 - 10E-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022498(6-Chloro-3,4-dihydro-2H-benzo[h]chromene-4-carboxy...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022492(8-chlorospiro[3,4-dihydro-2H-chromene-4,4'-(tetrah...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022471(5,7,8-trimethylspiro[3,4-dihydro-2H-chromene-4,4'-...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022423(7'-chlorospiro[tetrahydro-1H-imidazole-4,4'-(3',4'...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022422(6-methylsulfanylspiro[3,4-dihydro-2H-chromene-4,4'...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of partially purified calf lens aldose reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022459(6'-fluorospiro[tetrahydro-1H-imidazole-4,4'-(3',4'...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory activity towards partially purified calf lens aldose reductase; value ranges from 10E-6 - 10E-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022434(CHEMBL81601 | spiro[tetrahydro-1H-imidazole-4,4'-(...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory activity towards partially purified calf lens aldose reductase; value ranges from 10E-6 - 10E-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022436(CHEMBL312392 | spiro[tetrahydro-1H-imidazole-4,1'-...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory activity towards partially purified calf lens aldose reductase; value ranges from 10E-6 - 10E-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022407(6'-fluorospiro[tetrahydro-1H-imidazole-4,4'-(3',4'...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory activity towards partially purified calf lens aldose reductase; value ranges from 10E-6 - 10E-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50022398((+)-6-chloro-2,3-dihydro-2'H,4'H-spiro[chromene-4,...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory activity towards partially purified calf lens aldose reductase; value ranges from 10E-6 - 10E-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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