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Found 50 with Last Name = 'schulte' and Initial = 'mk'
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
The University Of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50103072(1-Benzyl-2-piperazin-1-yl-1H-benzoimidazole | CHEM...)
Affinity DataKi:  0.360nMAssay Description:Binding affinity of the compound against human 5-hydroxytryptamine 3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
The University Of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50103070(1-(4-Methoxy-benzyl)-2-piperazin-1-yl-1H-benzoimid...)
Affinity DataKi:  0.420nMAssay Description:Binding affinity of the compound against human 5-hydroxytryptamine 3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
The University Of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50103076(1-Naphthalen-2-ylmethyl-2-piperazin-1-yl-1H-benzoi...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity of the compound against human 5-hydroxytryptamine 3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
The University Of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50103075(1-(4-Methyl-benzyl)-2-piperazin-1-yl-1H-benzoimida...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity of the compound against human 5-hydroxytryptamine 3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
The University Of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50103069(1-(4-Fluoro-benzyl)-2-piperazin-1-yl-1H-benzoimida...)
Affinity DataKi:  5.20nMAssay Description:Binding affinity of the compound against human 5-hydroxytryptamine 3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
The University Of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50103073(1-Phenethyl-2-piperazin-1-yl-1H-benzoimidazole | C...)
Affinity DataKi:  7.40nMAssay Description:Binding affinity of the compound against human 5-hydroxytryptamine 3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
The University Of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50103071(1-(3-Phenyl-propyl)-2-piperazin-1-yl-1H-benzoimida...)
Affinity DataKi:  8nMAssay Description:Binding affinity of the compound against human 5-hydroxytryptamine 3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
The University Of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50103077(2-Piperazin-1-yl-1H-benzoimidazole | CHEMBL292066)
Affinity DataKi:  19nMAssay Description:Binding affinity of the compound against human 5-hydroxytryptamine 3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
The University Of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50053608(1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]GR65630 from 5-HT3 receptor (unknown origin) expressed in mouse/rat NG108-15 cells after 30 mins by by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
The University Of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50441458(CHEMBL2436555)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]GR65630 from 5-HT3 receptor (unknown origin) expressed in mouse/rat NG108-15 cells after 30 mins by by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
The University Of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50441458(CHEMBL2436555)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]GR65630 from human 5-HT3 receptor expressed in African green monkey COS cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
The University Of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50115644((+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-tri...)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [3H]GR65630 from human 5-HT3A receptor expressed in HEK293 cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50441458(CHEMBL2436555)
Affinity DataKi:  6.15E+3nMAssay Description:Displacement of [3H]Pentazocine from guinea pig sigma1 receptor after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50441458(CHEMBL2436555)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Pyrilamine from human recombinant histamine H1 receptor expressed in HEK cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50441458(CHEMBL2436555)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-epibatidine from human alpha2beta4 nAChR transfected in HEK293 cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50441458(CHEMBL2436555)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [[3H]N-methylspiperone from human recombinant dopamine D2 receptor expressed in human fibroblasts after 90 mins by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50441458(CHEMBL2436555)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-epibatidine from human alpha4beta2 nAChR transfected in HEK293 cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50441458(CHEMBL2436555)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-epibatidine from human alpha2beta2 nAChR transfected in HEK293 cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50217055(CHEMBL1835612 | CHEMBL231592 | N-(2-[6-bromo-2(1,1...)
Affinity DataIC50:  4.40E+4nMAssay Description:Activity at human alpha7 nACh receptor expressesed in Xenopus oocytes assessed as inhibition of acetyl chlone-induced currents by two-electrode volta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50217055(CHEMBL1835612 | CHEMBL231592 | N-(2-[6-bromo-2(1,1...)
Affinity DataIC50:  1.50E+5nMAssay Description:Activity at human alpha4beta2 nACh receptor expressesed in Xenopus oocytes assessed as inhibition of acetyl chlone-induced currents by two-electrode ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50217054(CHEMBL230348 | desformylflustrabromine-B)
Affinity DataIC50:  2.09E+5nMAssay Description:Activity at human alpha7 nACh receptor expressesed in Xenopus oocytes assessed as inhibition of acetyl chlone-induced currents by two-electrode volta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419278(CHEMBL1835616)
Affinity DataEC50:  2.95E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two-electrode voltag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419270(CHEMBL1835618)
Affinity DataEC50:  7.76E+3nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two-electrode voltag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419271(CHEMBL1835619)
Affinity DataEC50:  2.04E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two-electrode voltag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419277(CHEMBL1835687)
Affinity DataEC50:  4.47E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two-electrode voltag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419273(CHEMBL1835688)
Affinity DataEC50:  4.79E+3nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two-electrode voltag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419269(CHEMBL1835617)
Affinity DataEC50:  2.57E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two-electrode voltag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419276(CHEMBL1835686)
Affinity DataEC50:  9.77E+3nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two-electrode voltag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419275(CHEMBL1835615)
Affinity DataEC50:  2.09E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two-electrode voltag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419274(CHEMBL1835614)
Affinity DataEC50:  1.10E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two-electrode voltag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419272(CHEMBL1835613)
Affinity DataEC50:  5.75E+3nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two-electrode voltag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50217055(CHEMBL1835612 | CHEMBL231592 | N-(2-[6-bromo-2(1,1...)
Affinity DataEC50:  1.86E+3nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two-electrode voltag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419277(CHEMBL1835687)
Affinity DataEC50:  1.86E+4nMAssay Description:Antagonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two electrode v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419276(CHEMBL1835686)
Affinity DataEC50:  1.66E+4nMAssay Description:Antagonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two electrode v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419275(CHEMBL1835615)
Affinity DataEC50:  7.24E+4nMAssay Description:Antagonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two electrode v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419274(CHEMBL1835614)
Affinity DataEC50:  3.98E+4nMAssay Description:Antagonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two electrode v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419273(CHEMBL1835688)
Affinity DataEC50:  3.98E+3nMAssay Description:Agonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as potentiation of acetylcholine-induced current by two electrode vo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419271(CHEMBL1835619)
Affinity DataEC50:  1.22E+3nMAssay Description:Agonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as potentiation of acetylcholine-induced current by two electrode vo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419270(CHEMBL1835618)
Affinity DataEC50:  7.24E+3nMAssay Description:Agonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as potentiation of acetylcholine-induced current by two electrode vo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419269(CHEMBL1835617)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as potentiation of acetylcholine-induced current by two electrode vo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419272(CHEMBL1835613)
Affinity DataEC50:  513nMAssay Description:Agonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as potentiation of acetylcholine-induced current by two electrode vo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50217055(CHEMBL1835612 | CHEMBL231592 | N-(2-[6-bromo-2(1,1...)
Affinity DataEC50:  331nMAssay Description:Agonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as potentiation of acetylcholine-induced current by two electrode vo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419271(CHEMBL1835619)
Affinity DataEC50:  1.22E+3nMAssay Description:Agonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as potentiation of acetylcholine-induced current by two electrode vo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419270(CHEMBL1835618)
Affinity DataEC50:  6.77E+3nMAssay Description:Agonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as potentiation of acetylcholine-induced current by two electrode vo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419269(CHEMBL1835617)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as potentiation of acetylcholine-induced current by two electrode vo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50419278(CHEMBL1835616)
Affinity DataEC50:  3.55E+3nMAssay Description:Antagonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as inhibition of acetylcholine-induced current by two electrode v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Mus musculus (house mouse))
Virtua Drug

Curated by ChEMBL
LigandPNGBDBM50053615(3-Chloro-Phenyl biguanide | CHEMBL13790 | N-(3-chl...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at wild type mouse 5HT3A receptor expressed in Xenopus oocyte by two-electrode voltage patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Mus musculus (house mouse))
Virtua Drug

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataEC50:  3.40E+3nMAssay Description:Agonist activity at wild type mouse 5HT3A receptor expressed in Xenopus oocyte by two-electrode voltage patch clamp methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
The University Of Louisiana At Monroe

Curated by ChEMBL
LigandPNGBDBM50103074(1-Allyl-2-piperazin-1-yl-1H-benzoimidazole | CHEMB...)
Affinity DataEC50:  240nMAssay Description:Binding affinity of the compound against human 5-hydroxytryptamine 3A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50217055(CHEMBL1835612 | CHEMBL231592 | N-(2-[6-bromo-2(1,1...)
Affinity DataEC50:  320nMAssay Description:Agonist activity at human alpha4beta2 nACHR expressed in xenopus oocyte assessed as potentiation of acetylcholine-induced current by two electrode vo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed