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Found 43 with Last Name = 'sierecki' and Initial = 'e'
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328826(5-((E)-(4-((E)-(2,4-diamino-5-methylphenyl)diazeny...)
Affinity DataIC50:  3.75E+3nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328821(1-amino-9,10-dioxo-4-(3-sulfamoylphenylamino)-9,10...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328818(6-methoxy-N-(2-(piperidin-2-yl)ethyl)quinolin-8-am...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328820(1-((4-methoxyphenylamino)methyl)naphthalen-2-ol | ...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50172540([2-(4-Amino-benzoyloxy)-ethyl]-dimethyl-ammonium)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328824(1,3-di(1H-indazol-6-yl)thiourea | CHEMBL1269022 | ...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328822(4-((3-hydroxypyridin-2-yl)diazenyl)benzenesulfonam...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50246208(2-(3,4,5-trihydroxy-6-oxo-6H-xanthen-9-yl)cyclohex...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM25462(2,3-dinitro-9H-fluoren-9-one | NSC133896)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM54340(4-[4-(3-chlorophenyl)-1-piperazinyl]-3-methylisoxa...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328827(5-((E)-(4-((E)-(2,4-diamino-5-methyl-3-((E)-(4-met...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328823(5,5'-(3-(pyridin-2-yl)-1,2,4-triazine-5,6-diyl)dif...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328819(4-bromobenzenesulfonic(8S,9S,10R,13S,14S,17S)-10,1...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328828(8-amino-5-((E)-(4'-((E)-(4-amino-6-(methylsulfonyl...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328829(5-(4'-((2,4-diamino-5-((4-sulfophenyl)diazenyl)phe...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328830(2-hydroxy-3-((4-(N-thiazol-2-ylsulfamoyl)phenyl)di...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328831(2-hydroxy-5-((E)-(2-methoxy-4-((E)-(4-sulfophenyl)...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50079267(Congo Red | Direct red 28 | Kongorot | Sodium diph...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328832(2-hydroxy-3-((4-(N-pyridin-2-ylsulfamoyl)phenyl)di...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328833(4-(6-chloro-2-methoxyacridin-9-ylamino)-2-hydroxyb...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328834(3-((4'-((6-amino-1-hydroxy-3-sulfonaphthalen-2-yl)...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328825(9-benzyl-6-(benzylthio)-9H-purin-2-amine | CHEMBL1...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328835(4-(4-acetamidophenylamino)-1-amino-9,10-dioxo-9,10...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328836(4-(6-chloro-2-methoxyacridin-9-ylamino)benzoic aci...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328837(2-hydroxy-5-((4'-((1-hydroxy-3-(methylsulfonyl)-7-...)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328838(2-hydroxy-5-((4-(N-thiazol-2-ylsulfamoyl)phenyl)di...)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328839(2-hydroxy-5-((4'-((1-hydroxy-3-(methylsulfonyl)-6-...)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328840(5-amino-4-hydroxy-3-((4'-((1-hydroxy-4-sulfonaphth...)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50190337(5-{[4-(aminosulfonyl)phenyl]diazenyl}-2-hydroxyben...)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328841(5-amino-4-hydroxy-3-((4-(4-((2-hydroxy-8-sulfonaph...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPH domain leucine-rich repeat-containing protein phosphatase 2(Homo sapiens (Human))
University Of California San Diego

Curated by ChEMBL
LigandPNGBDBM50328842(2-hydroxy-3-methyl-5-((4-((4-sulfophenyl)diazenyl)...)
Affinity DataIC50:  8.30E+4nMAssay Description:Inhibition of PHLPP2 phosphatase domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM223293(Sm4 | US20240002326, Compound Sm4)
Affinity DataIC50:  9.75E+4nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM223299(Sm14 | US20240002326, Compound Sm14)
Affinity DataIC50:  1.20E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50:  1.63E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataIC50:  2.20E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM223295(Sm8 | US20240002326, Compound Sm8)
Affinity DataIC50:  3.27E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM50259931(6-Tridecylsalicylic acid (Sm2) | 6-tridecyl phenol...)
Affinity DataIC50:  3.41E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM223292(6-Undecylsalicylic acid (Sm1) | US20240002326, Com...)
Affinity DataIC50:  3.48E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM85507(CAS_4394-00-7 | NSC_4488 | Niflumic acid | Niflumi...)
Affinity DataIC50:  3.75E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM223298(Sm13 | US20240002326, Compound Sm13)
Affinity DataIC50:  4.81E+5nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM223294(Sm5)
Affinity DataIC50:  1.11E+6nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM223297(Sm12 | US20240002326, Compound Sm12)
Affinity DataIC50:  2.88E+6nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor SOX-18(Mus musculus (Mouse))
The University of Queensland

LigandPNGBDBM223296(Sm11 | US20240002326, Compound Sm11)
Affinity DataIC50:  3.80E+6nMpH: 7.5 T: 2°CAssay Description:The DNA-binding competition assay was performed in 25 μL, in black 384-well plates, using either 30 mM HEPES (N-2-Hydroxyethylpiperazine-N'-2-Etha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed