Affinity DataKi: 0.129nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.263nMAssay Description:Displacement [3H]prazosin of human recombinant alpha1A adrenergic receptor expressed in CHO cells by rapid filtration techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
Affinity DataKi: 0.331nMAssay Description:Displacement [3H]8-OH-DPAT of human cloned 5HT1A receptor expressed in human HeLa cells by rapid filtration techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 0.331nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
Affinity DataKi: 0.420nMAssay Description:Inhibitory constant against dopamine D2 receptor using 0.2 nM [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Inhibitory constant against sigma receptor type 2 using 3 nM [3H]ditolylguanidineMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Homo sapiens (Human))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 0.590nMAssay Description:Displacement of [3H]-ditolylguanidine from human Sigma 2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]-pentazocine from human Sigma 1 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibitory constant was determined against 5-hydroxytryptamine 1A receptor using 1.2 nM [3H]8-OH-DPATMore data for this Ligand-Target Pair
Affinity DataKi: 0.603nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.603nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Displacement [3H]prazosin of human recombinant alpha1A adrenergic receptor expressed in CHO cells by rapid filtration techniqueMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 0.740nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.776nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
Affinity DataKi: 0.813nMAssay Description:Displacement of [3H]prazosin from recombinant human alpha1d adrenergic receptor expressed in CHO cell membranes after 30 mins by TopCount liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 0.813nMAssay Description:Displacement [3H]prazosin of human recombinant Alpha-1D adrenergic receptor expressed in CHO cells by rapid filtration techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 0.871nMAssay Description:Displacement [3H]prazosin of human recombinant alpha1A adrenergic receptor expressed in CHO cells by rapid filtration techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 0.891nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.912nMAssay Description:Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.933nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 1.02nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H] prazosin from human cloned adrenoceptor alpha 1D expressed in CHO cell membrane incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Displacement [3H]8-OH-DPAT of human cloned 5HT1A receptor expressed in human HeLa cells by rapid filtration techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Displacement [3H]8-OH-DPAT of human cloned 5HT1A receptor expressed in human HeLa cells by rapid filtration techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 1.29nMAssay Description:Displacement [3H]prazosin of human recombinant Alpha-1D adrenergic receptor expressed in CHO cells by rapid filtration techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 1.29nMAssay Description:Displacement of [3H]prazosin from human Alpha-1D adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT-1AR transfected in HeLa cells incubated for 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Modena And Reggio Emilia
Curated by ChEMBL
University Of Modena And Reggio Emilia
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HeLa cell membranes after 30 mins by TopCount liquid scintillation ...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]prazosin from recombinant human alpha1d adrenergic receptor expressed in CHO cell membranes after 30 mins by TopCount liquid scin...More data for this Ligand-Target Pair
Affinity DataKi: 1.38nMAssay Description:Displacement [3H]prazosin of human recombinant Alpha-1D adrenergic receptor expressed in CHO cells by rapid filtration techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 1.38nMAssay Description:Displacement [3H]prazosin of human recombinant alpha1A adrenergic receptor expressed in CHO cells by rapid filtration techniqueMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibitory constant against sigma receptor type 2 using 3 nM [3H]ditolylguanidineMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
Affinity DataKi: 1.48nMAssay Description:Inhibitory constant against sigma receptor type 2 using 3 nM [3H]ditolylguanidineMore data for this Ligand-Target Pair
Affinity DataKi: 1.48nMAssay Description:Displacement [3H]prazosin of human recombinant Alpha-1D adrenergic receptor expressed in CHO cells by rapid filtration techniqueMore data for this Ligand-Target Pair