Compile Data Set for Download or QSAR
maximum 50k data
Found 2667 with Last Name = 'sorensen' and Initial = 'bk'
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50051007((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbam...)
Affinity DataKi:  0.0340nMAssay Description:Inhibitory activity of the compound against human Endothelin A receptor in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50106407(1-Dibutylcarbamoylmethyl-4-(2,3-dihydro-benzofuran...)
Affinity DataKi:  0.0390nMAssay Description:Binding affinity against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50051007((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbam...)
Affinity DataKi:  0.0470nMAssay Description:binding affinity against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050976(4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2...)
Affinity DataKi:  0.0690nMAssay Description:Inhibitory activity of the compound against human Endothelin A receptor in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050964(4-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenes...)
Affinity DataKi:  0.130nMAssay Description:Inhibitory activity of the compound against human Endothelin A receptor in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50034267(3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methox...)
Affinity DataKi:  0.170nMAssay Description:Inhibitory activity of the compound against human Endothelin A receptor in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50041617((1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymet...)
Affinity DataKi:  0.430nMAssay Description:Inhibitory activity of the compound against human Endothelin A receptor in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50066391((2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-(2,2-dimethy...)
Affinity DataKi:  0.460nMAssay Description:Binding affinity against endothelin A receptor in MMQ cells in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM217096(US9302989, 391)
Affinity DataKi:  0.490nMAssay Description:HTRF assay: This assay used the CisBio HTRF KinEASE kit (kit 62ST2PEZ) and the kinase reaction containing 0.2 uM biotinylated substrate peptide (S2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM217112(US9302989, 407)
Affinity DataKi:  1nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM217092(US9302989, 387)
Affinity DataKi:  1.39nMAssay Description:HTRF assay: This assay used the CisBio HTRF KinEASE kit (kit 62ST2PEZ) and the kinase reaction containing 0.2 uM biotinylated substrate peptide (S2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50254198(CHEMBL4060799)
Affinity DataKi:  1.5nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM217057(US9302989, 349)
Affinity DataKi:  1.60nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50254199(CHEMBL4083505)
Affinity DataKi:  1.70nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM217094(US9302989, 389)
Affinity DataKi:  1.74nMAssay Description:HTRF assay: This assay used the CisBio HTRF KinEASE kit (kit 62ST2PEZ) and the kinase reaction containing 0.2 uM biotinylated substrate peptide (S2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50254216(CHEMBL4096471)
Affinity DataKi:  1.90nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202094(CHEMBL375341 | N-(5-hydroxy-adamantan-2-yl)-2-(3-t...)
Affinity DataKi:  2nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM217103(US9302989, 398)
Affinity DataKi:  2.20nMAssay Description:HTRF assay: This assay used the CisBio HTRF KinEASE kit (kit 62ST2PEZ) and the kinase reaction containing 0.2 uM biotinylated substrate peptide (S2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM217085(US9302989, 380)
Affinity DataKi:  2.30nMAssay Description:HTRF assay: This assay used the CisBio HTRF KinEASE kit (kit 62ST2PEZ) and the kinase reaction containing 0.2 uM biotinylated substrate peptide (S2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM217083(US9302989, 378)
Affinity DataKi:  2.37nMAssay Description:HTRF assay: This assay used the CisBio HTRF KinEASE kit (kit 62ST2PEZ) and the kinase reaction containing 0.2 uM biotinylated substrate peptide (S2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM217084(US9302989, 379)
Affinity DataKi:  2.40nMAssay Description:HTRF assay: This assay used the CisBio HTRF KinEASE kit (kit 62ST2PEZ) and the kinase reaction containing 0.2 uM biotinylated substrate peptide (S2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM217095(US9302989, 390)
Affinity DataKi:  2.45nMAssay Description:HTRF assay: This assay used the CisBio HTRF KinEASE kit (kit 62ST2PEZ) and the kinase reaction containing 0.2 uM biotinylated substrate peptide (S2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50254215(CHEMBL4089003)
Affinity DataKi:  2.5nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144020(3-{4-[1-(4-Benzofuran-2-yl-phenylcarbamoyl)-heptyl...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM217040(US9302989, 332)
Affinity DataKi:  3nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50435350(CHEMBL17289)
Affinity DataKi:  3nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202094(CHEMBL375341 | N-(5-hydroxy-adamantan-2-yl)-2-(3-t...)
Affinity DataKi:  3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM81395(APO-866)
Affinity DataKi:  3nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202094(CHEMBL375341 | N-(5-hydroxy-adamantan-2-yl)-2-(3-t...)
Affinity DataKi:  3nMAssay Description:Inhibitory activity against rat 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM217324(US9302989, 549)
Affinity DataKi:  3.10nMAssay Description:HTRF assay: This assay used the CisBio HTRF KinEASE kit (kit 62ST2PEZ) and the kinase reaction containing 0.2 uM biotinylated substrate peptide (S2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM217320(US9302989, 374)
Affinity DataKi:  3.60nMAssay Description:HTRF assay: This assay used the CisBio HTRF KinEASE kit (kit 62ST2PEZ) and the kinase reaction containing 0.2 uM biotinylated substrate peptide (S2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM217088(US9302989, 383)
Affinity DataKi:  3.61nMAssay Description:HTRF assay: This assay used the CisBio HTRF KinEASE kit (kit 62ST2PEZ) and the kinase reaction containing 0.2 uM biotinylated substrate peptide (S2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50254212(CHEMBL4076064)
Affinity DataKi:  3.90nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202085((R)-N-[(E)-5-hydroxy-2-adamantyl]-2-{4-[5-(trifluo...)
Affinity DataKi:  4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202102(CHEMBL375156 | N-(5-Hydroxy-adamantan-2-yl)-2-[4-(...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against rat 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202087(CHEMBL374728 | N-[(1R,3S)-5-hydroxy-2-adamantyl]-2...)
Affinity DataKi:  4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202085((R)-N-[(E)-5-hydroxy-2-adamantyl]-2-{4-[5-(trifluo...)
Affinity DataKi:  4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144008(3-{4-[2-(4-Benzofuran-2-yl-phenylcarbamoyl)-2-(4-t...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity against human glucagon receptor (h-GlucR) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM217086(US9302989, 381)
Affinity DataKi:  4.12nMAssay Description:HTRF assay: This assay used the CisBio HTRF KinEASE kit (kit 62ST2PEZ) and the kinase reaction containing 0.2 uM biotinylated substrate peptide (S2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM217089(US9302989, 384)
Affinity DataKi:  4.24nMAssay Description:HTRF assay: This assay used the CisBio HTRF KinEASE kit (kit 62ST2PEZ) and the kinase reaction containing 0.2 uM biotinylated substrate peptide (S2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50254192(CHEMBL4105475)
Affinity DataKi:  4.30nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM215830(US9302989, 25)
Affinity DataKi:  4.70nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM217170(US9302989, 608)
Affinity DataKi:  4.90nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202085((R)-N-[(E)-5-hydroxy-2-adamantyl]-2-{4-[5-(trifluo...)
Affinity DataKi:  5nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202085((R)-N-[(E)-5-hydroxy-2-adamantyl]-2-{4-[5-(trifluo...)
Affinity DataKi:  5nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202087(CHEMBL374728 | N-[(1R,3S)-5-hydroxy-2-adamantyl]-2...)
Affinity DataKi:  5nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202102(CHEMBL375156 | N-(5-Hydroxy-adamantan-2-yl)-2-[4-(...)
Affinity DataKi:  5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202105(CHEMBL218093 | N-adamantan-2-yl-2-[4-(4-chloro-phe...)
Affinity DataKi:  5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202093(2-[3-(2-fluoro-phenoxy)-azetidin-1-yl]-N-(5-hydrox...)
Affinity DataKi:  5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50254214(CHEMBL4086819)
Affinity DataKi:  5.10nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 2667 total ) | Next | Last >>
Jump to: