TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Inhibition of rolipram binding to Phosphodiesterase 4More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 2.60E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 2.80E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: >3.70E+3nMAssay Description:Displacement of [3H]rolipram binding to guinea pig brain membraneMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Aventis Pharma
Curated by ChEMBL
Aventis Pharma
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of p38-related TNF alpha release by human monocyte cell line (THP-1)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Aventis Pharma
Curated by ChEMBL
Aventis Pharma
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of p38-related TNF alpha release by human monocyte cell line (THP-1)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Aventis Pharma
Curated by ChEMBL
Aventis Pharma
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of p38-related TNF alpha release by human monocyte cell line (THP-1)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Aventis Pharma
Curated by ChEMBL
Aventis Pharma
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of p38-related TNF alpha release by human monocyte cell line (THP-1)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of guinea pig macrophage Phosphodiesterase 4More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Aventis Pharma
Curated by ChEMBL
Aventis Pharma
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of p38-related TNF alpha release by human monocyte THP-1 cell linesMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against p38 kinase (40 ng/well) was determined in mouseMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Aventis Pharma
Curated by ChEMBL
Aventis Pharma
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of p38-related TNF alpha release by human monocyte cell line (THP-1)More data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair