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Found 733 with Last Name = 'stürzebecher' and Initial = 'j'
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211565((R)-N-[(S)-1-(2-aminomethyl-5-chloro-benzylcarbamo...)
Affinity DataKi:  0.0330nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211578((S)-1-[(R)-4-(1-oxy-pyridin-2-yl)-2-phenylmethanes...)
Affinity DataKi:  0.0490nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211567((R)-N-[(S)-1-(2-aminomethyl-5-chloro-benzylcarbamo...)
Affinity DataKi:  0.0590nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211585(CHEMBL389960 | [(R)-1-[(S)-2-(2-aminomethyl-5-chlo...)
Affinity DataKi:  0.0800nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211571((R)-N-((S)-1-(2-(aminomethyl)-5-chlorobenzylamino)...)
Affinity DataKi:  0.0840nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211564((R)-N-[(5-chloro-2-ethyl-benzylcarbamoyl)-methyl]-...)
Affinity DataKi:  0.0950nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211563((S)-4-(2-aminomethyl-5-chloro-benzylcarbamoyl)-4-{...)
Affinity DataKi:  0.240nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211570(CHEMBL228984 | N-((S)-1-(2-(aminomethyl)-5-chlorob...)
Affinity DataKi:  0.25nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211582((R)-N-[(4-carbamimidoyl-benzylcarbamoyl)-methyl]-4...)
Affinity DataKi:  0.320nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211552((4-{[1-{[(2-aminomethyl-5-chloro-benzylcarbamoyl)-...)
Affinity DataKi:  0.350nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211572((4-{[1-{[(2-aminomethyl-5-chloro-benzylcarbamoyl)-...)
Affinity DataKi:  0.360nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211586((s)-4-(2-aminomethyl-5-chloro-benzylcarbamoyl)-4-[...)
Affinity DataKi:  0.520nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211578((S)-1-[(R)-4-(1-oxy-pyridin-2-yl)-2-phenylmethanes...)
Affinity DataKi:  0.560nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211587(CHEMBL427464 | N-[(R)-1-[(S)-2-(2-aminomethyl-5-ch...)
Affinity DataKi:  0.630nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211584(CHEMBL231393 | [1-{[(2-aminomethyl-5-chloro-benzyl...)
Affinity DataKi:  0.760nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211551(CHEMBL228285 | N-[1-[(S)-2-(2-aminomethyl-5-chloro...)
Affinity DataKi:  0.870nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211576(CHEMBL228341 | [(R)-1-[(S)-2-(2-aminomethyl-5-chlo...)
Affinity DataKi:  0.920nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211556(CHEMBL390402 | [(R)-1-[(S)-2-(2-aminomethyl-5-chlo...)
Affinity DataKi:  0.940nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211577(CHEMBL229036 | [(R)-1-[(S)-2-(2-aminomethyl-5-chlo...)
Affinity DataKi:  1nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211581(2-((R)-1-((S)-2-((2-(aminomethyl)-5-chlorobenzyl)c...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211580(CHEMBL231494 | [1-{[(2-aminomethyl-5-chloro-benzyl...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211566(CHEMBL228340 | [(R)-1-[(S)-2-(2-aminomethyl-5-chlo...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060017(3-[(R)-3-(4-Methanesulfonyl-piperazin-1-yl)-2-(nap...)
Affinity DataKi:  2.10nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060036(3-[(R)-3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-...)
Affinity DataKi:  2.5nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211555(CHEMBL397679 | N-[(2,5-dichloro-benzylcarbamoyl)-m...)
Affinity DataKi:  2.55nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211573(CHEMBL390403 | ethyl 2-((R)-1-((S)-2-((2-(aminomet...)
Affinity DataKi:  2.90nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211562(2-((R)-1-((S)-2-((2-(aminomethyl)-5-chlorobenzyl)c...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50110023(2-(3-Hydroxy-2-phenylmethanesulfonylamino-propiony...)
Affinity DataKi:  3.20nMAssay Description:In vitro inhibition of trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060014(3-[3-(4-Methanesulfonyl-piperazin-1-yl)-2-(naphtha...)
Affinity DataKi:  3.30nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211575((R)-N-[(3-chloro-benzylcarbamoyl)-methyl]-4-(1-oxy...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50110025(CHEMBL158405 | N-(BENZYLSULFONYL)-D-SERYL-N-{4-[AM...)
Affinity DataKi:  3.30nMAssay Description:In vitro inhibition of trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211560(CHEMBL231292 | N-[(2-aminomethyl-5-chloro-benzylca...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211581(2-((R)-1-((S)-2-((2-(aminomethyl)-5-chlorobenzyl)c...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211559(CHEMBL230360 | ethyl 2-((R)-1-((S)-2-((2-(aminomet...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211573(CHEMBL390403 | ethyl 2-((R)-1-((S)-2-((2-(aminomet...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060035(4-[(R)-3-(3-Carbamimidoyl-phenyl)-2-(naphthalene-2...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060027(3-[2-(4-tert-Butyl-benzenesulfonylamino)-3-(4-meth...)
Affinity DataKi:  4.30nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50110016(CHEMBL433510 | Carbonic acid 2-[1-(4-carbamimidoyl...)
Affinity DataKi:  4.80nMAssay Description:In vitro inhibition of trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211568(CHEMBL395773 | N-[1-{[(2-aminomethyl-5-chloro-benz...)
Affinity DataKi:  4.90nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211557(CHEMBL231595 | N-[1-{[(2-aminomethyl-5-chloro-benz...)
Affinity DataKi:  4.90nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211566(CHEMBL228340 | [(R)-1-[(S)-2-(2-aminomethyl-5-chlo...)
Affinity DataKi:  4.90nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060019(3-[(R)-3-(4-Methanesulfonyl-piperazin-1-yl)-3-oxo-...)
Affinity DataKi:  5.30nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50072840(CHEMBL346607 | N-[1-(4-Diaminomethyl-benzyl)-2-oxo...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against bovine thrombin expressed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060033(3-[3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-2-su...)
Affinity DataKi:  6.20nMAssay Description:Inhibitory activity against bovine thrombin expressed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060033(3-[3-(4-Methyl-piperidin-1-yl)-2-(naphthalene-2-su...)
Affinity DataKi:  6.20nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50041224((R)-3-(7-Carbamimidoyl-naphthalen-2-yl)-2-{4-[(S)-...)
Affinity DataKi:  7nMAssay Description:Binding affinity of the compound towards Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50060039(3-[3-(4-Methanesulfonyl-piperazin-1-yl)-3-oxo-2-(2...)
Affinity DataKi:  7.40nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Universitat Jena

Curated by ChEMBL
LigandPNGBDBM50110025(CHEMBL158405 | N-(BENZYLSULFONYL)-D-SERYL-N-{4-[AM...)
Affinity DataKi:  7.70nMAssay Description:In vitro inhibition of plasminogen activator urokinase.More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Curacyte Discovery

Curated by ChEMBL
LigandPNGBDBM50211585(CHEMBL389960 | [(R)-1-[(S)-2-(2-aminomethyl-5-chlo...)
Affinity DataKi:  7.70nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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