TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain
Curated by ChEMBL
University Of Louvain
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain
Curated by ChEMBL
University Of Louvain
Curated by ChEMBL
Affinity DataKi: 47nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain
Curated by ChEMBL
University Of Louvain
Curated by ChEMBL
Affinity DataKi: 54nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain
Curated by ChEMBL
University Of Louvain
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain
Curated by ChEMBL
University Of Louvain
Curated by ChEMBL
Affinity DataKi: 72nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain
Curated by ChEMBL
University Of Louvain
Curated by ChEMBL
Affinity DataKi: 72nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain
Curated by ChEMBL
University Of Louvain
Curated by ChEMBL
Affinity DataKi: 365nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain
Curated by ChEMBL
University Of Louvain
Curated by ChEMBL
Affinity DataKi: 571nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Louvain
Curated by ChEMBL
University Of Louvain
Curated by ChEMBL
Affinity DataKi: 628nMAssay Description:The compound was tested for the affinity on sigma 1 receptor using [3H]- pentazocine as radioligandMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Howard University
Curated by ChEMBL
Howard University
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of tetrodotoxin-sensitive Na+ channel at -50 mV membrane holding potential by patch-clamp electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Howard University
Curated by ChEMBL
Howard University
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.06E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University
Curated by ChEMBL
Acadia University
Curated by ChEMBL
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tetrodotoxin-sensitive Na+ channel by patch-clamp electrophysiologyMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Howard University
Curated by ChEMBL
Howard University
Curated by ChEMBL
Affinity DataIC50: 1.14E+5nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Howard University
Curated by ChEMBL
Howard University
Curated by ChEMBL
Affinity DataIC50: 1.31E+5nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Howard University
Curated by ChEMBL
Howard University
Curated by ChEMBL
Affinity DataIC50: 1.52E+5nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Howard University
Curated by ChEMBL
Howard University
Curated by ChEMBL
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University
Curated by ChEMBL
Acadia University
Curated by ChEMBL
Affinity DataIC50: 2.03E+5nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University
Curated by ChEMBL
Acadia University
Curated by ChEMBL
Affinity DataIC50: 2.46E+5nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University
Curated by ChEMBL
Acadia University
Curated by ChEMBL
Affinity DataIC50: 4.32E+5nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University
Curated by ChEMBL
Acadia University
Curated by ChEMBL
Affinity DataIC50: 4.34E+5nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Howard University
Curated by ChEMBL
Howard University
Curated by ChEMBL
Affinity DataIC50: 4.89E+5nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University
Curated by ChEMBL
Acadia University
Curated by ChEMBL
Affinity DataIC50: 1.60E+6nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University
Curated by ChEMBL
Acadia University
Curated by ChEMBL
Affinity DataIC50: 2.33E+6nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University
Curated by ChEMBL
Acadia University
Curated by ChEMBL
Affinity DataIC50: 2.56E+6nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University
Curated by ChEMBL
Acadia University
Curated by ChEMBL
Affinity DataIC50: 4.38E+6nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University
Curated by ChEMBL
Acadia University
Curated by ChEMBL
Affinity DataIC50: 7.55E+6nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University
Curated by ChEMBL
Acadia University
Curated by ChEMBL
Affinity DataIC50: >8.00E+6nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University
Curated by ChEMBL
Acadia University
Curated by ChEMBL
Affinity DataIC50: 8.35E+6nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University
Curated by ChEMBL
Acadia University
Curated by ChEMBL
Affinity DataIC50: >1.00E+7nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Acadia University
Curated by ChEMBL
Acadia University
Curated by ChEMBL
Affinity DataIC50: 4.00E+8nMAssay Description:Inhibition of human NMT expressed in Escherichia coli DH5alpha cellsMore data for this Ligand-Target Pair