TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.0420nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO/HEK293 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.0680nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.0860nMAssay Description:Affinity for displacement of [125I]-iodoproxyfan from human histamine H3 receptors stably expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.0910nMAssay Description:Affinity for displacement of [125I]-iodoproxyfan from human histamine H3 receptors stably expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.0933nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.0940nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.0940nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Inhibition of [125I]-iodoproxyfan from rat histamine H3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:In vitro inhibitory activity against Histamine H3 receptor for K+ evoked depolarization-induced release of [3H]-histamine from synaptosomes of rat ce...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.126nMAssay Description:Displacement of [3H]N-alpha-Methylhistamine from human recombinant H3 receptor expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in HEK293 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Binding affinity to human H3RMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]-spiperone from human dopamine D3 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.229nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human H3 receptor expressed in HEK-293 cell membrane after 90 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO/HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.275nMAssay Description:Binding affinity to human H3RMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H] N-alpha methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells measured after 90 minsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Modulation of human D2L receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to human H3RMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]spiperone from human D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of human H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.310nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H] N-alpha methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells measured after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Binding affinity for human dopamine receptor D3 by displacing [125I]-iodosulpiride expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.330nMAssay Description:Affinity for displacement of [125I]-iodoproxyfan from human histamine H3 receptors stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Binding affinity to human D3 receptor expressed in CHO cells assessed as inhibition constant by scintillation counting methodMore data for this Ligand-Target Pair
Ligand Info
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.358nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHO/HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Binding affinity for human dopamine receptor D3 by displacing [125I]-iodosulpiride expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Johann Wolfgang Goethe-UniversitäT
Curated by ChEMBL
Johann Wolfgang Goethe-UniversitäT
Curated by ChEMBL
Affinity DataKi: 0.390nMAssay Description:Binding affinity of compound towards human Dopamine receptor D4 by displacing [125I]-iodosulpiride expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.420nMAssay Description:Binding affinity to human H3R expressed in rat C6 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Binding affinity for human dopamine receptor D3 by displacing [125I]-iodosulpiride expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Binding affinity for human dopamine receptor D3 by displacing [125I]-iodosulpiride expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.More data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Binding affinity for human dopamine receptor D3 by displacing [125I]-iodosulpiride expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Binding affinity for human dopamine receptor D3 by displacing [125I]-iodosulpiride expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Johann Wolfgang Goethe Universit£T
Curated by ChEMBL
Affinity DataKi: 0.479nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair