Affinity DataKi: 0.200nM ΔG°: -54.8kJ/mole EC50: 19nMpH: 7.6 T: 2°CAssay Description:Binding assays were conducted by incubating test compound at various concentrations with [3H]DHT with human cancer epithelial breast cell lines MDAMB...More data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -53.8kJ/mole EC50: 1.40nMpH: 7.6 T: 2°CAssay Description:Binding assays were conducted by incubating test compound at various concentrations with [3H]DHT with human cancer epithelial breast cell lines MDAMB...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -53.8kJ/mole EC50: 0.200nMpH: 7.6 T: 2°CAssay Description:Binding assays were conducted by incubating test compound at various concentrations with [3H]DHT with human cancer epithelial breast cell lines MDAMB...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -53.8kJ/mole EC50: 14nMpH: 7.6 T: 2°CAssay Description:Binding assays were conducted by incubating test compound at various concentrations with [3H]DHT with human cancer epithelial breast cell lines MDAMB...More data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -52.6kJ/mole EC50: 2nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -51.7kJ/mole EC50: 2.60nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -51.7kJ/mole EC50: 3.70nMpH: 7.6 T: 2°CAssay Description:Binding assays were conducted by incubating test compound at various concentrations with [3H]DHT with human cancer epithelial breast cell lines MDAMB...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nM ΔG°: -51.4kJ/mole EC50: 4.80nMpH: 7.6 T: 2°CAssay Description:Binding assays were conducted by incubating test compound at various concentrations with [3H]DHT with human cancer epithelial breast cell lines MDAMB...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -51.1kJ/mole EC50: 2.5nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -51.1kJ/mole EC50: 1.80nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/mole EC50: 2.90nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nM ΔG°: -50.0kJ/mole EC50: 0.700nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nM ΔG°: -49.9kJ/mole EC50: 5.20nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nM ΔG°: -49.7kJ/mole EC50: 5.40nMpH: 7.6 T: 2°CAssay Description:Binding assays were conducted by incubating test compound at various concentrations with [3H]DHT with human cancer epithelial breast cell lines MDAMB...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nM ΔG°: -49.7kJ/mole EC50: 7.10nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nM ΔG°: -49.3kJ/mole EC50: 44nMpH: 7.6 T: 2°CAssay Description:Binding assays were conducted by incubating test compound at various concentrations with [3H]DHT with human cancer epithelial breast cell lines MDAMB...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nM ΔG°: -49.3kJ/mole EC50: 48nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.2kJ/mole EC50: 15nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
Affinity DataKi: 2.11nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nM ΔG°: -48.9kJ/mole EC50: 20nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
Affinity DataKi: 2.20nM ΔG°: -48.9kJ/mole EC50: 2.10nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nM ΔG°: -48.8kJ/mole EC50: 7.40nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nM ΔG°: -48.8kJ/mole EC50: 1.10nMpH: 7.6 T: 2°CAssay Description:Binding assays were conducted by incubating test compound at various concentrations with [3H]DHT with human cancer epithelial breast cell lines MDAMB...More data for this Ligand-Target Pair
Affinity DataKi: 2.90nM ΔG°: -48.2kJ/mole EC50: 13nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus after 18 hrs by scintillation counting anal...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nM ΔG°: -48.0kJ/mole EC50: 2.30nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]DHT from human androgen receptor in MDA453 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus after 18 hrs by scintillation counting anal...More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.5kJ/mole EC50: 87nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus after 18 hrs by scintillation counting anal...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [beta-33P]-2MeS-ADP from human P2Y1 receptor expressed in HEK293 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6nM ΔG°: -46.5kJ/mole EC50: 6.40nMpH: 7.6 T: 2°CAssay Description:Binding assays were conducted by incubating test compound at various concentrations with [3H]DHT with human cancer epithelial breast cell lines MDAMB...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of [3H]dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus after 18 hrs by scintillation counting anal...More data for this Ligand-Target Pair