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Found 322 with Last Name = 'taglialatela-scafati' and Initial = 'o'
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  0.450nM ΔG°:  -54.2kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  7.5nM ΔG°:  -47.2kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  9.20nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29079(cyclopropanolamide, 12a | cyclopropanolamide, rac-...)
Affinity DataKi:  11nM ΔG°:  -46.2kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM22988((5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-...)
Affinity DataKi:  11nM ΔG°:  -46.2kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50180036((6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetra...)
Affinity DataKi:  13nM ΔG°:  -45.8kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29078(cyclopropanolamide, 13a | cyclopropanolamide, rac-...)
Affinity DataKi:  14nM ΔG°:  -45.6kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29087(cyclopropanolamide, 14a)
Affinity DataKi:  20nM ΔG°:  -44.7kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29078(cyclopropanolamide, 13a | cyclopropanolamide, rac-...)
Affinity DataKi:  27nM ΔG°:  -43.9kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29088(cyclopropanolamide, 11a)
Affinity DataKi:  28nM ΔG°:  -43.8kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29079(cyclopropanolamide, 12a | cyclopropanolamide, rac-...)
Affinity DataKi:  32nM ΔG°:  -43.5kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29078(cyclopropanolamide, 13a | cyclopropanolamide, rac-...)
Affinity DataKi:  150nM ΔG°:  -39.6kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM22988((5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-...)
Affinity DataKi:  168nM ΔG°:  -39.3kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50353094(CHEMBL1823117)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29079(cyclopropanolamide, 12a | cyclopropanolamide, rac-...)
Affinity DataKi:  190nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29087(cyclopropanolamide, 14a)
Affinity DataKi:  190nM ΔG°:  -39.0kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29078(cyclopropanolamide, 13a | cyclopropanolamide, rac-...)
Affinity DataKi:  200nM ΔG°:  -38.9kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29079(cyclopropanolamide, 12a | cyclopropanolamide, rac-...)
Affinity DataKi:  240nM ΔG°:  -38.4kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29088(cyclopropanolamide, 11a)
Affinity DataKi:  290nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29081(cyclopropanolamide, 13b | cyclopropanolamide, rac-...)
Affinity DataKi:  340nM ΔG°:  -37.5kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29082(cyclopropanolamide, 12b | cyclopropanolamide, rac-...)
Affinity DataKi:  380nM ΔG°:  -37.3kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29082(cyclopropanolamide, 12b | cyclopropanolamide, rac-...)
Affinity DataKi:  570nM ΔG°:  -36.2kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29081(cyclopropanolamide, 13b | cyclopropanolamide, rac-...)
Affinity DataKi:  600nM ΔG°:  -36.1kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM113765((E)-N-Allyl-6-((1R,2R)-3,3-dimethyl-2-(3-methylbut...)
Affinity DataKi:  680nM ΔG°:  -35.8kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29081(cyclopropanolamide, 13b | cyclopropanolamide, rac-...)
Affinity DataKi:  700nM ΔG°:  -35.7kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29082(cyclopropanolamide, 12b | cyclopropanolamide, rac-...)
Affinity DataKi:  700nM ΔG°:  -35.7kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50353094(CHEMBL1823117)
Affinity DataKi:  750nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50318487(CHEMBL497318 | Cannabigerol)
Affinity DataKi:  760nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50318487(CHEMBL497318 | Cannabigerol)
Affinity DataKi:  760nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29091(cyclopropanolamide, 14b)
Affinity DataKi:  820nM ΔG°:  -35.3kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50318487(CHEMBL497318 | Cannabigerol)
Affinity DataKi:  880nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM113764((E)-6-((1R,2R)-3,3-Dimethyl-2-(3-methylbut-3-enyl)...)
Affinity DataKi:  1.01E+3nM ΔG°:  -34.8kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29080(CHEMBL280065 | N-oleoylethanolamine | Oleamide MEA...)
Affinity DataKi:  1.10E+3nM ΔG°:  -34.6kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29093(cyclopropanolamide, 11b)
Affinity DataKi:  1.40E+3nM ΔG°:  -34.0kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM113766((E)-N-(2-Chloroethyl)-6-((1R,2R)-3,3-dimethyl-2-(3...)
Affinity DataKi:  1.43E+3nM ΔG°:  -33.9kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29091(cyclopropanolamide, 14b)
Affinity DataKi:  1.63E+3nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29081(cyclopropanolamide, 13b | cyclopropanolamide, rac-...)
Affinity DataKi:  2.04E+3nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29093(cyclopropanolamide, 11b)
Affinity DataKi:  2.42E+3nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM113764((E)-6-((1R,2R)-3,3-Dimethyl-2-(3-methylbut-3-enyl)...)
Affinity DataKi:  3.66E+3nM ΔG°:  -31.6kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM113766((E)-N-(2-Chloroethyl)-6-((1R,2R)-3,3-dimethyl-2-(3...)
Affinity DataKi:  3.83E+3nM ΔG°:  -31.4kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29082(cyclopropanolamide, 12b | cyclopropanolamide, rac-...)
Affinity DataKi:  4.41E+3nMAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29083(Impulsin | MimyX | Palmidrol | Palmityoletanolamid...)
Affinity DataKi: >5.00E+3nM ΔG°: >-30.8kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29083(Impulsin | MimyX | Palmidrol | Palmityoletanolamid...)
Affinity DataKi: >5.00E+3nM ΔG°: >-30.8kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM113768((E)-N-(3,4-Dihydroxyphenethyl)-6-((1R,2R)-3,3-dime...)
Affinity DataKi:  6.50E+3nM ΔG°:  -30.1kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM113765((E)-N-Allyl-6-((1R,2R)-3,3-dimethyl-2-(3-methylbut...)
Affinity DataKi:  8.64E+3nM ΔG°:  -29.4kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29085(cyclopropanolamide, rac-9c)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.0kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29084(cyclopropanolamide, rac-10c | racemic)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.0kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29080(CHEMBL280065 | N-oleoylethanolamine | Oleamide MEA...)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.0kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University of Bern

LigandPNGBDBM29084(cyclopropanolamide, rac-10c | racemic)
Affinity DataKi: >1.00E+4nM ΔG°: >-29.0kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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