TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Binding affinity to PRMT5 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataKi: <0.0700nMAssay Description:Binding affinity to DOT1L (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataKi: <0.100nMAssay Description:Binding affinity to EZH2 Y641N mutant (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Binding affinity to EZH2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Binding affinity to DOT1L (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataKi: 194nMAssay Description:Binding affinity to EZH2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataKi: 290nMAssay Description:Binding affinity to DOT1L (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 9.80E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate complex state after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 1.10E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate complex state after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 1.50E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate complex state after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 1.60E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate complex state after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 1.80E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate complex state after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 1.90E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate complex state after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 2.10E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate complex state after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 3.80E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-inhibitor complex state after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 5.80E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate-inhibitor complex state after 30 mins by fluorescence assa...More data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 7.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-inhibitor complex state after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 9.90E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-inhibitor complex state after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 1.25E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate-inhibitor complex state after 30 mins by fluorescence assa...More data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 2.60E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-inhibitor complex state after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 4.34E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate-inhibitor complex state after 30 mins by fluorescence assa...More data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 5.18E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate-inhibitor complex state after 30 mins by fluorescence assa...More data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 5.63E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate-inhibitor complex state after 30 mins by fluorescence assa...More data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 5.72E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate-inhibitor complex state after 30 mins by fluorescence assa...More data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 7.23E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate-inhibitor complex state after 30 mins by fluorescence assa...More data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 8.32E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-inhibitor complex state after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: 8.32E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-inhibitor complex state after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Target6,7-dimethyl-8-ribityllumazine synthase(Mycobacterium tuberculosis)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant lumazine synthase at enzyme-substrate-inhibitor complex state after 30 mins by fluorescence assa...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 0.0320nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 0.0570nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant DOT1L (unknown origin) using 3H-SAM/chicken erythrocyte nucleosomes as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Chk1 (unknown origin) expressed in Sf9 insect cells using biotinylated cdc25c peptide as substrate in presence of 33P-gamma-labeled ATP...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant DOT1L (unknown origin) using 3H-SAM/chicken erythrocyte nucleosomes as substrate preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of DOT1L (unknown origin)More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 0.330nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of DOT1L (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at AT1 receptor in rat aortic ringsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at AT1 receptor in rat aortic ringsMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.77nMAssay Description:Assay buffer (4 μL) was added into all the wells, including test compound and control wells (except for Sinefungin control wells), using the Mul...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.07nMAssay Description:Assay buffer (4 μL) was added into all the wells, including test compound and control wells (except for Sinefungin control wells), using the Mul...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Assay buffer (4 μL) was added into all the wells, including test compound and control wells (except for Sinefungin control wells), using the Mul...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Csir-Indian Institute Of Chemical Biology
Curated by ChEMBL
Affinity DataIC50: <2.5nMAssay Description:Inhibition of PRMT7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.71nMAssay Description:Assay buffer (4 μL) was added into all the wells, including test compound and control wells (except for Sinefungin control wells), using the Mul...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Assay buffer (4 μL) was added into all the wells, including test compound and control wells (except for Sinefungin control wells), using the Mul...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Assay buffer (4 μL) was added into all the wells, including test compound and control wells (except for Sinefungin control wells), using the Mul...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Assay buffer (4 μL) was added into all the wells, including test compound and control wells (except for Sinefungin control wells), using the Mul...More data for this Ligand-Target Pair