TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataKi: 47nMAssay Description:Binding affinity to MCHR1More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.490nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.820nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.910nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.920nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair