TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
Mahidol University
Mahidol University
Affinity DataKi: 0.0110nM ΔG°: -62.5kJ/mole IC50: 0.570nMpH: 7.0 T: 2°CAssay Description:The concentration of inhibitor that inhibited 50% of the parasite growth (IC50) was determined from the sigmoidal curve obtained by plotting the perc...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
Mahidol University
Mahidol University
Affinity DataKi: 0.0200nM ΔG°: -61.1kJ/mole IC50: 2.30nMpH: 7.0 T: 2°CAssay Description:The concentration of inhibitor that inhibited 50% of the parasite growth (IC50) was determined from the sigmoidal curve obtained by plotting the perc...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [N51I,C59R,S108N,I164L](Plasmodium falciparum (isolate K1 / Thailand))
Mahidol University
Mahidol University
Affinity DataKi: 0.0370nM ΔG°: -59.5kJ/mole IC50: 18nMpH: 7.0 T: 2°CAssay Description:The concentration of inhibitor that inhibited 50% of the parasite growth (IC50) was determined from the sigmoidal curve obtained by plotting the perc...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
Mahidol University
Mahidol University
Affinity DataKi: 0.200nM ΔG°: -55.4kJ/mole IC50: 80nMpH: 7.0 T: 2°CAssay Description:The concentration of inhibitor that inhibited 50% of the parasite growth (IC50) was determined from the sigmoidal curve obtained by plotting the perc...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
Mahidol University
Mahidol University
Affinity DataKi: 0.300nM ΔG°: -54.4kJ/mole IC50: 37nMpH: 7.0 T: 2°CAssay Description:The concentration of inhibitor that inhibited 50% of the parasite growth (IC50) was determined from the sigmoidal curve obtained by plotting the perc...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nM ΔG°: -49.9kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University of Michigan
Curated by PDSP Ki Database
University of Michigan
Curated by PDSP Ki Database
Affinity DataKi: 2nM ΔG°: -48.8kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University of Michigan
Curated by PDSP Ki Database
University of Michigan
Curated by PDSP Ki Database
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University of Michigan
Curated by PDSP Ki Database
University of Michigan
Curated by PDSP Ki Database
Affinity DataKi: 4nM ΔG°: -47.1kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
Mahidol University
Mahidol University
Affinity DataKi: 6.20nM ΔG°: -46.8kJ/mole IC50: 2.40E+3nMpH: 7.0 T: 2°CAssay Description:The concentration of inhibitor that inhibited 50% of the parasite growth (IC50) was determined from the sigmoidal curve obtained by plotting the perc...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 7.20nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 7.40nM ΔG°: -45.6kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ul of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: 8nM ΔG°: -45.4kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
Mahidol University
Mahidol University
Affinity DataKi: 9.80nM ΔG°: -45.7kJ/mole IC50: 3.09E+4nMpH: 7.0 T: 2°CAssay Description:The concentration of inhibitor that inhibited 50% of the parasite growth (IC50) was determined from the sigmoidal curve obtained by plotting the perc...More data for this Ligand-Target Pair
Affinity DataKi: 13nM ΔG°: -44.3kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: 13nM ΔG°: -44.3kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: 16nM ΔG°: -43.8kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: 18nM ΔG°: -43.5kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: 20nM ΔG°: -43.2kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-25-hydroxycholesterol from human N-terminal 6His-tagged-RORC2 LBD (259 to 483 residues) expressed in Escherichia coli (DE3) cell...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-25-hydroxycholesterol from human N-terminal 6His-tagged-RORC2 LBD (259 to 483 residues) expressed in Escherichia coli (DE3) cell...More data for this Ligand-Target Pair
Affinity DataKi: 24nM ΔG°: -42.8kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: 25nM ΔG°: -42.7kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: 26nM ΔG°: -42.6kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: 30nM ΔG°: -42.2kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: 30nM ΔG°: -42.2kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University of Michigan
Curated by PDSP Ki Database
University of Michigan
Curated by PDSP Ki Database
Affinity DataKi: 40nM ΔG°: -41.5kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: 40nM ΔG°: -41.5kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: 40nM ΔG°: -41.5kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 42nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]-25-hydroxycholesterol from human N-terminal 6His-tagged-RORC2 LBD (259 to 483 residues) expressed in Escherichia coli (DE3) cell...More data for this Ligand-Target Pair
Affinity DataKi: 50nM ΔG°: -41.0kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: 50nM ΔG°: -41.0kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
Affinity DataKi: 50nM ΔG°: -41.0kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair