Affinity DataKi: 49nMAssay Description:Competitive inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinoline formation using varying levels of kynuramine as substra...More data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Competitive inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinoline formation using varying levels of kynuramine as substra...More data for this Ligand-Target Pair
Affinity DataKi: 124nMAssay Description:Mixed-type inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinoline formation using varying levels of kynuramine as substrat...More data for this Ligand-Target Pair
Affinity DataKi: 163nMAssay Description:Mixed-type inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinoline formation using varying levels of kynuramine as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC8 (unknown origin) after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Plasmodium falciparum HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of Plasmodium falciparum HDAC1More data for this Ligand-Target Pair
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of Plasmodium falciparum HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant MAO-B using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 109nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 121nMAssay Description:Inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of Plasmodium falciparum HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
Affinity DataIC50: 143nMAssay Description:Inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
Affinity DataIC50: 148nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant MAOB assessed as conversion of kynuramine to 4-hydroxyquinoline preincubated for 15 mins by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 153nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 165nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 207nMAssay Description:Inhibition of human recombinant MAO-B using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 213nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 226nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 236nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 238nMAssay Description:Inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
Affinity DataIC50: 263nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 267nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of Plasmodium falciparum HDAC1More data for this Ligand-Target Pair
TargetHistone deacetylase(Plasmodium falciparum (isolate 3D7))
Georgia Institute Of Technology
Curated by ChEMBL
Georgia Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 304nMAssay Description:Inhibition of Plasmodium falciparum HDAC1More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
Affinity DataIC50: 327nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 364nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 366nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of human recombinant MAO-B using kynuramine as substrate preincubated with compound for 15 mins measured after 20 mins by fluorometric ana...More data for this Ligand-Target Pair