Compile Data Set for Download or QSAR
maximum 50k data
Found 204 with Last Name = 'terrett' and Initial = 'nk'
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50399909(CHEMBL2180945)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50287545(4-[4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50161957(4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(p...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of recombinant EGFR (unknown origin) after 10 mins by DELFIA/time-resolved fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286792((R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4...)
Affinity DataIC50:  2.5nMAssay Description:Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50399893(CHEMBL2180948)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50112346(CHEMBL3609325)
Affinity DataIC50:  3nMAssay Description:Inhibition of cIAP BIR2-3 domain (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Ensemble Therapeutics

Curated by ChEMBL
LigandPNGBDBM50078359(CHEMBL3414729)
Affinity DataIC50:  3nMAssay Description:Inhibition of cIAP1 BIR2-3 (154 to 352 residues) (unknown origin) fluoresceinated dimeric SMAC peptide based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50112346(CHEMBL3609325)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of XIAP BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50399891(CHEMBL2180950)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50399894(CHEMBL2180947)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Ensemble Therapeutics

Curated by ChEMBL
LigandPNGBDBM50078360(CHEMBL3414728)
Affinity DataIC50:  5nMAssay Description:Inhibition of cIAP1 BIR2-3 (154 to 352 residues) (unknown origin) fluoresceinated dimeric SMAC peptide based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286804((R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4...)
Affinity DataIC50:  5.30nMAssay Description:Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50287543(5-(2-ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-1-me...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of Phosphodiesterase 5 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50399896(CHEMBL2180943)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129516(CHEMBL71918 | N-[2-(3,4-Dichloro-phenyl)-4-piperid...)
Affinity DataIC50:  6.30nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129511(2-Cyclopropyl-1-{3-(3,4-dichloro-phenyl)-3-[2-(3-m...)
Affinity DataIC50:  6.30nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129509(CHEMBL69065 | N-[2-(3,4-Dichloro-phenyl)-4-(4-hydr...)
Affinity DataIC50:  6.40nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129506(CHEMBL308901 | {3-(3,4-Dichloro-phenyl)-3-[2-(3-mo...)
Affinity DataIC50:  6.5nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129517(CHEMBL307338 | N-{2-(3,4-Dichloro-phenyl)-4-[4-hyd...)
Affinity DataIC50:  6.60nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50399898(CHEMBL2180941)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129519(4-(1-{2-[1-Benzenesulfonyl-3-(3,4-dichloro-phenyl)...)
Affinity DataIC50:  6.70nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129508(CHEMBL305191 | N-[2-(3,4-Dichloro-phenyl)-4-(4-[1,...)
Affinity DataIC50:  6.80nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129510(CHEMBL71704 | N-[2-(3,4-Dichloro-phenyl)-4-(3-imid...)
Affinity DataIC50:  6.80nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Ensemble Therapeutics

Curated by ChEMBL
LigandPNGBDBM50078354(CHEMBL3414727)
Affinity DataIC50:  7nMAssay Description:Inhibition of cIAP1 BIR2-3 (154 to 352 residues) (unknown origin) fluoresceinated dimeric SMAC peptide based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129520(CHEMBL69335 | N-[2-(3,4-Dichloro-phenyl)-4-(4-phen...)
Affinity DataIC50: <7nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129518(CHEMBL71394 | N-{2-(3,4-Dichloro-phenyl)-4-[3-(2-o...)
Affinity DataIC50:  7.10nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50399897(CHEMBL2180942)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129514(CHEMBL71644 | {3-(3,4-Dichloro-phenyl)-3-[2-(3-mor...)
Affinity DataIC50:  7.20nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129512(CHEMBL304807 | N-[4-[4-(1H-Benzoimidazol-2-yl)-pip...)
Affinity DataIC50:  7.30nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129515(CHEMBL71226 | N-{2-(3,4-Dichloro-phenyl)-4-[3-(2-o...)
Affinity DataIC50:  7.40nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129505(CHEMBL69889 | {3-(3,4-Dichloro-phenyl)-3-[2-(3-mor...)
Affinity DataIC50:  7.5nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129522(CHEMBL68917 | N-[2-(3,4-Dichloro-phenyl)-4-(4-imid...)
Affinity DataIC50:  7.70nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129521(CHEMBL71647 | N-[2-(3,4-Dichloro-phenyl)-4-(3-morp...)
Affinity DataIC50:  7.70nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286795((R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4...)
Affinity DataIC50:  8nMAssay Description:Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286800((R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4...)
Affinity DataIC50:  8nMAssay Description:Binding affinity against ETA receptor from dog spleen membranes using [125I]-ET1 as radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50078358(CHEMBL3414723)
Affinity DataIC50:  8nMAssay Description:Inhibition of cIAP1 BIR3 (154 to 352 residues) (unknown origin) by fluoresceinated dimeric SMAC peptide based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129507(CHEMBL305236 | N-[4-(4-Benzoimidazol-1-yl-piperidi...)
Affinity DataIC50:  8.10nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129524(CHEMBL74127 | N-{2-(3,4-Dichloro-phenyl)-4-[4-(2-o...)
Affinity DataIC50:  8.40nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50399890(CHEMBL2180951)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129513(CHEMBL71397 | N-[2-(3,4-Dichloro-phenyl)-4-(4-hydr...)
Affinity DataIC50:  8.90nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50129523(CHEMBL68440 | N-{2-(3,4-Dichloro-phenyl)-4-[4-(2-o...)
Affinity DataIC50:  8.90nMAssay Description:Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50071112(CHEMBL56835 | N-[4-(4-Acetylamino-4-phenyl-piperid...)
Affinity DataIC50:  8.90nMAssay Description:Binding affinity towards human Tachykinin receptor 2 using [125I]- NKA radioligand expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Ensemble Therapeutics

Curated by ChEMBL
LigandPNGBDBM50078359(CHEMBL3414729)
Affinity DataIC50:  9nMAssay Description:Inhibition of XIAP BIR2-3 (125 to 356 residues) C202A/C213G mutant (unknown origin) fluoresceinated dimeric SMAC peptide based fluorescence polarizat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50078359(CHEMBL3414729)
Affinity DataIC50:  10nMAssay Description:Inhibition of cIAP1 BIR3 (154 to 352 residues) (unknown origin) by fluoresceinated dimeric SMAC peptide based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50078357(CHEMBL3414724)
Affinity DataIC50:  11nMAssay Description:Inhibition of cIAP1 BIR3 (154 to 352 residues) (unknown origin) by fluoresceinated dimeric SMAC peptide based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50399887(CHEMBL2180954)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50399910(CHEMBL2180944)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant PDE5A by [3H]cGMP based tritium scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 204 total ) | Next | Last >>
Jump to: