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Found 909 with Last Name = 'tomita' and Initial = 'k'
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

US Patent
LigandPNGBDBM107307(US8592379, 19)
Affinity DataIC50:  0.120nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

US Patent
LigandPNGBDBM26339((2R,3E)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)
Affinity DataIC50:  0.120nMAssay Description:Displacement of [125I]kisspeptin-15 from GPR54More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

US Patent
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)
Affinity DataIC50:  0.120nMAssay Description:Displacement of [125I]kisspeptin-15 from GPR54More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

US Patent
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)
Affinity DataIC50:  0.120nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

US Patent
LigandPNGBDBM26339((2R,3E)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)
Affinity DataIC50:  0.120nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

US Patent
LigandPNGBDBM26347((2R,4S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)
Affinity DataIC50:  0.240nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

US Patent
LigandPNGBDBM107314(US8592379, 36 | US8592379, 37)
Affinity DataIC50:  0.240nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

US Patent
LigandPNGBDBM107306(US8592379, 1)
Affinity DataIC50:  0.710nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

US Patent
LigandPNGBDBM26338((2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoy...)
Affinity DataIC50:  0.710nMAssay Description:Displacement of [125I]kisspeptin-15 from GPR54More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

US Patent
LigandPNGBDBM26338((2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoy...)
Affinity DataIC50:  0.710nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336911((S)-2-((S)-2-((S)-5-amino-2-((S)-1-((S)-2-((S)-2-(...)
Affinity DataIC50:  0.790nMAssay Description:Displacement of (D-[125I]Tyr1, MePhe3)-NPFF from NPFFR2 after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

US Patent
LigandPNGBDBM26340((2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoy...)
Affinity DataIC50:  1.20nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

US Patent
LigandPNGBDBM107308(US8592379, 20)
Affinity DataIC50:  1.20nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336911((S)-2-((S)-2-((S)-5-amino-2-((S)-1-((S)-2-((S)-2-(...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of (D-[125I]Tyr1, MePhe3)-NPFF from NPFFR1 after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346986(US10202379, Reference Example 730)
Affinity DataIC50:  2.52nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346979(US10202379, Reference Example 719)
Affinity DataIC50:  2.60nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346964(US10202379, Reference Example 666)
Affinity DataIC50:  3.36nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346968(US10202379, Reference Example 691)
Affinity DataIC50:  3.67nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346984(US10202379, Reference Example 726)
Affinity DataIC50:  3.74nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

US Patent
LigandPNGBDBM26341((2E)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoy...)
Affinity DataIC50:  4.60nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

US Patent
LigandPNGBDBM107309(US8592379, 21)
Affinity DataIC50:  4.60nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuropeptide FF receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)
Affinity DataIC50:  4.70nMAssay Description:Displacement of (D-[125I]Tyr1, MePhe3)-NPFF from NPFFR1 after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346923(US10202379, Reference Example 602)
Affinity DataIC50:  5nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346931(US10202379, Reference Example 619)
Affinity DataIC50:  5nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein(Hepatitis C virus)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50508967(CHEMBL3944613)
Affinity DataIC50:  5nMAssay Description:Inhibition of Influenza A virus CENMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346983(US10202379, Reference Example 724)
Affinity DataIC50:  5.07nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346995(US10202379, Reference Example 772)
Affinity DataIC50:  5.22nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346978(US10202379, Reference Example 716)
Affinity DataIC50:  5.54nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346976(US10202379, Reference Example 711)
Affinity DataIC50:  5.57nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

US Patent
LigandPNGBDBM107312(US8592379, 24a/24b | US8592379, 35)
Affinity DataIC50:  5.70nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

US Patent
LigandPNGBDBM26345((2R,4R)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)
Affinity DataIC50:  5.70nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346987(US10202379, Reference Example 731)
Affinity DataIC50:  5.76nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346994(US10202379, Reference Example 771)
Affinity DataIC50:  5.89nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346932(US10202379, Reference Example 621)
Affinity DataIC50:  6nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346980(US10202379, Reference Example 720 | US10202379, Re...)
Affinity DataIC50:  6.96nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346821(US10202379, Reference Example 446)
Affinity DataIC50:  7nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346840(US10202379, Reference Example 470)
Affinity DataIC50:  8nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346956(US10202379, Reference Example 654)
Affinity DataIC50:  8nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346917(US10202379, Reference Example 594)
Affinity DataIC50:  11nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein(Hepatitis C virus)
Shionogi

Curated by ChEMBL
LigandPNGBDBM105203(6-(4-Fluorophenyl)-3-hydroxy-5-[4-(1H-1, 2, 3, 4-t...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Influenza A virus CENMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346970(US10202379, Reference Example 704)
Affinity DataIC50:  11.1nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346837(US10202379, Reference Example 463)
Affinity DataIC50:  12nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346828(US10202379, Reference Example 454)
Affinity DataIC50:  12nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346965(US10202379, Reference Example 668)
Affinity DataIC50:  12.6nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346820(US10202379, Reference Example 445)
Affinity DataIC50:  13nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein(Hepatitis C virus)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50508966(CHEMBL4452342)
Affinity DataIC50:  14nMAssay Description:Inhibition of Influenza A virus CENMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346816(US10202379, Reference Example 433)
Affinity DataIC50:  14nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346744(US10202379, Reference Example 347)
Affinity DataIC50:  14nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346990(US10202379, Reference Example 752)
Affinity DataIC50:  14.2nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM346866(US10202379, Reference Example 509)
Affinity DataIC50:  15nMAssay Description:A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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