Affinity DataIC50: 0.400nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.450nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.490nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of DGAT1-mediated triacylglycerol synthesis in human HuTu80 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rat DGAT1More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant DGAT1 expressed in baculovirus infected insect sf9 cells using [14C] oleoyl coenzyme A after 30 mins by scintillation...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity to the human Neuropeptide Y receptor Y5 (NPY5)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity to the human Neuropeptide Y receptor Y5 (NPY5)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of mouse DGAT1More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity to the human Neuropeptide Y receptor Y5 (NPY5)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity to the human Neuropeptide Y receptor Y5 (NPY5)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity to the human Neuropeptide Y receptor Y5 (NPY5)More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Binding affinity to the human Neuropeptide Y receptor Y5 (NPY5)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Binding affinity to the human Neuropeptide Y receptor Y5 (NPY5)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Binding affinity to the human Neuropeptide Y receptor Y5 (NPY5)More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.66nMAssay Description:Inhibition of adipose tissue-derived 11beta-HSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human recombinant DGAT1 expressed in baculovirus infected insect sf9 cells using [14C] oleoyl coenzyme A after 30 mins by scintillation...More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length mouse 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length mouse 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human recombinant DGAT1 expressed in baculovirus infected insect sf9 cells using [14C] oleoyl coenzyme A after 30 mins by scintillation...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Compound was evaluated for functional antagonism of Neuropeptide Y receptor Y5 activity in cellular Ca fluxMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of N-terminal His-tagged full length human 11beta-HSD1 assessed as inhibition of cortisone to cortisol conversion preincubated for 25 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human recombinant DGAT1 expressed in baculovirus infected insect sf9 cells using [14C] oleoyl coenzyme A after 30 mins by scintillation...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human recombinant DGAT1 expressed in baculovirus infected insect sf9 cells using [14C] oleoyl coenzyme A after 30 mins by scintillation...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Binding affinity to the human Neuropeptide Y receptor Y5 (NPY5)More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Binding affinity against rat Neuropeptide Y receptor Y5More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length human 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of N-terminal 6-His-tagged full-length human 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Binding affinity to the human Neuropeptide Y receptor Y5 (NPY5)More data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysisMore data for this Ligand-Target Pair