Affinity DataKi: 3.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of carnitine in Xenopus laevis oocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 9.90nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of full-length human PDE4D2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human PDE4D (78 to 508)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyushu University
Curated by ChEMBL
Kyushu University
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of full-length human PDE4D2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 minsMore data for this Ligand-Target Pair