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Found 93 with Last Name = 'ujjinamatada' and Initial = 'r'
TargetAdenosine deaminase(Bos taurus (bovine))
University Of Maryland Baltimore County

LigandPNGBDBM21955(4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxym...)
Affinity DataKi:  1.06E+4nM ΔG°:  -28.4kJ/molepH: 7.0 T: 2°CAssay Description:The target compounds were screened against calf intestine ADA in vitro by monitoring the rate of hydrolyzing adenosine into inosine spectrophotometri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine deaminase(Bos taurus (bovine))
University Of Maryland Baltimore County

LigandPNGBDBM21953(4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)o...)
Affinity DataKi:  1.21E+4nM ΔG°:  -28.1kJ/molepH: 7.0 T: 2°CAssay Description:The target compounds were screened against calf intestine ADA in vitro by monitoring the rate of hydrolyzing adenosine into inosine spectrophotometri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGuanine deaminase(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50193757(3-benzyl-4,5,7,8-tetrahydro-6-hydroxymethyl-6H-imi...)
Affinity DataKi:  2.01E+4nMAssay Description:Inhibition of rabbit liver guanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine deaminase(Bos taurus (bovine))
University Of Maryland Baltimore County

LigandPNGBDBM21957(4-(hydrazinocarbonyl)-1-beta-D-ribofuranosyl-1H-im...)
Affinity DataKi:  2.65E+4nM ΔG°:  -26.1kJ/molepH: 7.0 T: 2°CAssay Description:The target compounds were screened against calf intestine ADA in vitro by monitoring the rate of hydrolyzing adenosine into inosine spectrophotometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine deaminase(Bos taurus (bovine))
University Of Maryland Baltimore County

LigandPNGBDBM21956(7-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxym...)
Affinity DataKi:  5.14E+4nM ΔG°:  -24.5kJ/molepH: 7.0 T: 2°CAssay Description:The target compounds were screened against calf intestine ADA in vitro by monitoring the rate of hydrolyzing adenosine into inosine spectrophotometri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine deaminase(Bos taurus (bovine))
University Of Maryland Baltimore County

LigandPNGBDBM21954(7-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)o...)
Affinity DataKi:  5.20E+4nM ΔG°:  -24.5kJ/molepH: 7.0 T: 2°CAssay Description:The target compounds were screened against calf intestine ADA in vitro by monitoring the rate of hydrolyzing adenosine into inosine spectrophotometri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGuanine deaminase(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50193756(4,5,7,8-tetrahydro-6-hydroxymethyl-6H-imidazo[4,5-...)
Affinity DataKi:  5.36E+4nMAssay Description:Inhibition of rabbit liver guanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247344(US9447091, 131)
Affinity DataIC50:  1.30nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247340(US9447091, 112)
Affinity DataIC50:  1.80nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247357(US9447091, 241)
Affinity DataIC50:  2.90nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247361(US9447091, 220)
Affinity DataIC50:  3.40nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247334(US9447091, 49)
Affinity DataIC50:  3.40nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247328(US9447091, 22)
Affinity DataIC50:  3.80nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247354(US9447091, 190)
Affinity DataIC50:  4.30nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247333(US9447091, 47)
Affinity DataIC50:  7nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247348(US9447091, 152)
Affinity DataIC50:  7.30nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247360(US9447091, 281)
Affinity DataIC50:  9nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247363(US9447091, 294)
Affinity DataIC50:  9.30nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247336(US9447091, 70)
Affinity DataIC50:  10nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247356(US9447091, 217)
Affinity DataIC50:  10.4nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247327(US9447091, 5)
Affinity DataIC50:  12nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247345(US9447091, 133)
Affinity DataIC50:  14nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247358(US9447091, 244)
Affinity DataIC50:  14nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247353(US9447091, 178)
Affinity DataIC50:  14.9nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247338(US9447091, 82)
Affinity DataIC50:  16nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247331(US9447091, 30)
Affinity DataIC50:  16nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247364(US9447091, 319)
Affinity DataIC50:  18nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247355(US9447091, 204)
Affinity DataIC50:  20nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247330(US9447091, 26)
Affinity DataIC50:  21nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247335(US9447091, 69)
Affinity DataIC50:  22nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247350(US9447091, 158)
Affinity DataIC50:  22nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247337(US9447091, 72)
Affinity DataIC50:  32nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247362(US9447091, 289)
Affinity DataIC50:  32nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247332(US9447091, 38)
Affinity DataIC50:  33nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247329(US9447091, 25)
Affinity DataIC50:  34nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247339(US9447091, 83)
Affinity DataIC50:  37nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247366(US9447091, 259)
Affinity DataIC50:  45nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247347(US9447091, 142)
Affinity DataIC50:  48nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247352(US9447091, 170)
Affinity DataIC50:  59nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247342(US9447091, 123)
Affinity DataIC50:  61nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247349(US9447091, 155)
Affinity DataIC50:  62nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247343(US9447091, 127)
Affinity DataIC50:  62nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247365(US9447091, 322)
Affinity DataIC50:  65.8nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247341(US9447091, 119)
Affinity DataIC50:  83nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247359(US9447091, 280)
Affinity DataIC50:  90nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247351(US9447091, 169)
Affinity DataIC50:  94nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Orion

US Patent
LigandPNGBDBM247346(US9447091, 134)
Affinity DataIC50:  98nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534623(2-(4-(ethylsulfonyl)phenyl)-N-(6-(4-methoxypyridin...)
Affinity DataIC50: <150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534619(2-(4-(ethylsulfonyl)phenyl)-N-(6-methyl-5-oxo-6-(p...)
Affinity DataIC50: <150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534631(N-(6-(benzo[d][1,3]dioxol-5-yl)-4,6-dimethyl-5-oxo...)
Affinity DataIC50: <150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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