Affinity DataKi: 0.200nM ΔG°: -51.5kJ/mole IC50: 0.200nM EC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Competitive Ligand Binding Assay- The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd) where [L] is the...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -48.9kJ/mole IC50: 1.10nM EC50: 5nMpH: 7.5 T: 2°CAssay Description:Competitive Ligand Binding Assay- The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd) where [L] is the...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -48.6kJ/mole IC50: 0.200nM EC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Competitive Ligand Binding Assay- The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd) where [L] is the...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nM ΔG°: -47.5kJ/mole IC50: 0.200nM EC50: 0.100nMpH: 7.5 T: 2°CAssay Description:Competitive Ligand Binding Assay- The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd) where [L] is the...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nM ΔG°: -47.3kJ/mole IC50: 1.60nM EC50: 1.30nMpH: 7.5 T: 2°CAssay Description:Competitive Ligand Binding Assay- The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd) where [L] is the...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nM ΔG°: -47.0kJ/mole IC50: 0.400nM EC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Competitive Ligand Binding Assay- The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd) where [L] is the...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nM ΔG°: -46.0kJ/mole IC50: 1.40nM EC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Competitive Ligand Binding Assay- The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd) where [L] is the...More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nM ΔG°: -44.3kJ/mole IC50: 6.10nM EC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Competitive Ligand Binding Assay- The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd) where [L] is the...More data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 57nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Binding affinity to androgen receptorMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Binding affinity to androgen receptorMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 346nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 370nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 380nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 430nMAssay Description:Binding affinity to androgen receptorMore data for this Ligand-Target Pair
Affinity DataKi: 570nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
Affinity DataKi: 670nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 790nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: 950nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
Affinity DataKi: 980nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair