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Found 241 with Last Name = 'verdie' and Initial = 'p'
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM21367(6-{4-[2-(methylsulfanyl)phenyl]piperazin-1-yl}-N-(...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50253281(CHEMBL522691 | N-(4-Cyanophenylmethyl)-4-(2-diphen...)
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003915(CHEMBL3235744)
Affinity DataKi: <1nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50098551((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003916(CHEMBL3235745)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50186245((2S)-1-[(adamantan-1-yl)carbonyl]-N-{4-[4-(2-metho...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50186236(Adamantane-1-carboxylic acid ((S)-1-{4-[4-(2-metho...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003945(CHEMBL3235739)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50267043(2-(2-(4-(3-chlorophenyl)piperazin-1-yl)ethyl)-2-az...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50261126(CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  4.60nMAssay Description:Binding affinity to 5HT1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50026916(2-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-2-a...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50297895(4-(2-methoxyphenyl)-N-(N-(naphthalen-1-ylmethyl)ca...)
Affinity DataKi:  6nMAssay Description:Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  6.05nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50206351((S)-N-(1-(4-(4-(3-chlorophenyl)piperazin-1-yl)buty...)
Affinity DataKi:  6.51nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50297894(2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4...)
Affinity DataKi:  8nMAssay Description:Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50186243(2-(bicyclo[2.2.1]heptan-2-yl)-N-((S)-1-(4-(4-(2-me...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003919(CHEMBL3235748)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003933(CHEMBL3235727)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50267043(2-(2-(4-(3-chlorophenyl)piperazin-1-yl)ethyl)-2-az...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003927(CHEMBL3235756)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50186255((S)-1-(cyclohexanecarbonyl)-N-(4-(4-(2-methoxyphen...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003929(CHEMBL3235758)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003914(CHEMBL3235743)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50186253((S)-1-(cyclohexanecarbonyl)-N-(4-(4-(2-methoxyphen...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50186244((S)-N-(1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)but...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50261126(CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  20nMAssay Description:Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003930(CHEMBL3235759)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003934(CHEMBL3235728)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50267016(CHEMBL514202 | N-[2-{4-(2-Methoxyphenyl)-piperazin...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50206351((S)-N-(1-(4-(4-(3-chlorophenyl)piperazin-1-yl)buty...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003931(CHEMBL3235760)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50297894(2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4...)
Affinity DataKi:  35nMAssay Description:Binding affinity to 5HT1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003942(CHEMBL3235736)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50186248(2-(bicyclo[2.2.1]heptan-2-yl)-N-((S)-1-(3-(4-(2-me...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50266905((S)-N-(1-(4-(4-(3-chlorophenyl)piperazin-1-yl)buty...)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003937(CHEMBL3235731)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003932(CHEMBL3235726)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50186243(2-(bicyclo[2.2.1]heptan-2-yl)-N-((S)-1-(4-(4-(2-me...)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50297896(CHEMBL561346 | N-[[(2-ethoxybenzyl)amino](imino)me...)
Affinity DataKi:  49nMAssay Description:Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003947(CHEMBL3235741)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003914(CHEMBL3235743)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003939(CHEMBL3235733)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM21367(6-{4-[2-(methylsulfanyl)phenyl]piperazin-1-yl}-N-(...)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50186250(Adamantane-1-carboxylic acid ((S)-1-{3-[4-(2-metho...)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50297894(2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4...)
Affinity DataKi:  65nMAssay Description:Binding affinity to 5HT2A receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50186242((S)-N-(1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)but...)
Affinity DataKi:  69nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003921(CHEMBL3235750)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50266905((S)-N-(1-(4-(4-(3-chlorophenyl)piperazin-1-yl)buty...)
Affinity DataKi:  75nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50003920(CHEMBL3235749)
Affinity DataKi:  77nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by beta-countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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