Found 1613 with Last Name = 'wagner' and Initial = 'ff' 
Affinity DataKi: <0.200nM ΔG°: <-55.4kJ/mole IC50: 1nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: <0.200nMAssay Description:Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged full length human recombinant HDAC1 expressed in baculovirus coexpressed in fall armyw...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nM ΔG°: -50.4kJ/mole IC50: 13nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition full length human recombinant HDAC2 expressed in baculovirus coexpressed in fall armyworm Sf9 cells using carboxyfluorescein (FAM)-labeled...More data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -48.6kJ/mole IC50: 2nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
Affinity DataKi: 14nM ΔG°: -44.8kJ/mole IC50: 19nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
Affinity DataKi: 25nM ΔG°: -43.4kJ/mole IC50: 46nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
Affinity DataKi: 29nM ΔG°: -43.0kJ/mole IC50: 64nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
Affinity DataKi: 37nM ΔG°: -42.4kJ/mole IC50: 41nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
Affinity DataKi: 84nMAssay Description:Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged full length human recombinant HDAC1 expressed in baculovirus coexpressed in fall armyw...More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 176nMAssay Description:Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged full length human recombinant HDAC1 expressed in baculovirus coexpressed in fall armyw...More data for this Ligand-Target Pair
Affinity DataKi: 223nM ΔG°: -38.0kJ/mole IC50: 147nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
Affinity DataKi: 500nM ΔG°: -36.0kJ/mole IC50: 398nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Inhibition full length human recombinant HDAC3 expressed in baculovirus using carboxyfluorescein (FAM)-labeled acetylated/ trifluoroacetylated peptid...More data for this Ligand-Target Pair
Affinity DataKi: 519nMAssay Description:Inhibition full length human recombinant HDAC2 expressed in baculovirus coexpressed in fall armyworm Sf9 cells using carboxyfluorescein (FAM)-labeled...More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
The Broad Institute Of Mit And Harvard
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Covalent inhibition of human PRMT5 assessed as initial binding constant by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.08E+3nMAssay Description:Inhibition full length human recombinant HDAC3 expressed in baculovirus using carboxyfluorescein (FAM)-labeled acetylated/ trifluoroacetylated peptid...More data for this Ligand-Target Pair
Affinity DataKi: 5.10E+3nM ΔG°: -30.2kJ/mole IC50: 1.08E+3nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
Affinity DataKi: 5.50E+3nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 5.50E+3nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 5.50E+3nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
Affinity DataKi: 5.50E+3nMAssay Description:The D2 binding Ki values were determined using a radioligand binding assay.More data for this Ligand-Target Pair
